Publications
Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.Biochem. Biophys. Res. Commun. 2013-04-10.
eIF4E3, a new actor in mRNA metabolism and tumor suppression.Cell Cycle 2013-04-09;12(8).
Aiding and abetting cancer: mRNA export and the nuclear pore.Trends Cell Biol. 2013-04-09.
The Oncogene eIF4E: Using Biochemical Insights to Target Cancer.J. Interferon Cytokine Res. 2013-03-08.
The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in Acute Myeloid Leukemia.Leukemia 2013-03-07.
eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition.Proc. Natl. Acad. Sci. U.S.A. 2013-02-19.
Mechanisms and insights into drug resistance in cancer.Front Pharmacol 2013-01-01;4:28.
MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo.Cancer Cell 2012-12-11;22(6):812-24.
The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation.Cell Rep 2012-08-14.
RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth.Oncogene 2012-07-16.

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