Matthew J. Smith, Ph.D.
- Principal Investigator, Cancer Signaling and Structural Biology research unit, IRIC
- Assistant Professor, Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal
Research topic and relevance
Matthew J. Smith and his group’s research aim to integrate modern experimental approaches in structural biology, biophysics, evolutionary bioinformatics, and cell biology to help identify and understand abnormal cancer signaling at both a mechanistic and systems level. In particular, they explore how genetic mutations correlate with altered structure in proteins and disrupted protein networks, triggering cell transformation and metastasis.