Principal Investigator

Michael Tyers

Systems Biology and Synthetic Biology

After earning his Ph.D. in Biochemistry at McMaster University, Michael Tyers completed postdoctoral training at the Cold Spring Harbor Laboratory, in New York. He began his career as a teacher in 1992, in the Department of Medical Genetics and Microbiology of the University of Toronto, then held the position of Principal Investigator at the Samuel Lunenfeld Research Institute. In 2007, he became Director of the Scottish Universities Life Sciences Alliance and taught systems biology at The University of Edinburgh.

Upon his return to Canada, he joined the IRIC as Principal Investigator of the Systems Biology and Synthetic Biology Research Unit. Michael Tyers is also a Professor in the Department of Medicine of the Université de Montréal.

Principal Investigator, Systems Biology and Synthetic Biology Research Unit, IRIC

Professor, Department of Medicine, Faculty of Medicine, Université de Montréal

Phone (office)
(514) 343-6111, ext. 6668
Email
md.tyers@umontreal.ca
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Systems Biology and Synthetic Biology

Michael Tyers and his team use biochemistry, genetics, chemical biology, microscopy, mass spectrometry and informatics to decipher how cellular networks are organized and controlled.

Research topics

Publications

  • July 8, 2019

    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.

    Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, Lavallée VP, Kanshin E, Bertomeu T, Coulombe-Huntington J, St-Denis C, Bordeleau ME, Boucher G, Roux PP, Lemieux S, Tyers M, Thibault P, Hébert J, Marinier A, Sauvageau G
    Cancer Cell 2019-07-08 ;36( 1 ):84-99.e8.

  • June 19, 2019

    Gene Information eXtension (GIX): effortless retrieval of gene product information on any website.

    Knight JDR, Samavarchi-Tehrani P, Tyers M, Gingras AC
    Nat. Methods 2019-06-19 ;.

  • April 1, 2019

    Proteome-wide, Structure-Based Prediction of Protein-Protein Interactions/New Molecular Interactions Viewer.

    Dong S, Lau V, Song R, Ierullo M, Esteban E, Wu Y, Sivieng T, Nahal H, Gaudinier A, Pasha A, Oughtred R, Dolinski K, Tyers M, Brady SM, Grene R, Usadel B, Provart NJ
    Plant Physiol. 2019-04-01 ;179( 4 ):1893-1907.

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News

  • July 8, 2019

    Treatment of leukemia: IRIC Investigators publish in Cancer Cell

    Researchers at UdeM have discovered a molecular process implicated in the action of anti-leukemia drugs, opening new avenues for the development of effective treatments for this disease.

  • November 13, 2018

    Renewal Michael Tyers’ Canada Research Chair

    Michael Tyers, Principal Investigator at IRIC and Professor at the Faculty of Medicine (Université de Montréal) obtained the renewal of his research chair in Systems and Synthetic Biology.

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