IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.

Chemogenetics defines receptor-mediated functions of short chain free fatty acids.Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan GNat. Chem. Biol. 2019-05-01;15(5):489-498.

Mild and Diazo-Free Synthesis of Trifluoromethyl-Cyclopropanes Using Sulfonium Ylides.Cyr P, Flynn-Robitaille J, Boissarie P, Marinier AOrg. Lett. 2019-04-05;21(7):2265-2268.

Identification of Allosteric Inhibitors against Active Caspase-6.Tubeleviciute-Aydin A, Beautrait A, Lynham J, Sharma G, Gorelik A, Deny LJ, Soya N, Lukacs GL, Nagar B, Marinier A, LeBlanc ACSci Rep 2019-04-02;9(1):5504.

Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells.Kobayashi H, Picard LP, Schönegge AM, Bouvier MNat Protoc 2019-04-01;14(4):1084-1107.

Proteome-wide, Structure-Based Prediction of Protein-Protein Interactions/New Molecular Interactions Viewer.Dong S, Lau V, Song R, Ierullo M, Esteban E, Wu Y, Sivieng T, Nahal H, Gaudinier A, Pasha A, Oughtred R, Dolinski K, Tyers M, Brady SM, Grene R, Usadel B, Provart NJPlant Physiol. 2019-04-01;179(4):1893-1907.

Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease.Lemieux C, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Roy J, Lachance SLeuk. Res. 2019-04-01;79:75-80.

Chemical shift assignment of the viral protein genome-linked (VPg) from potato virus Y.Coutinho de Oliveira L, Volpon L, Osborne MJ, Borden KLBBiomol NMR Assign 2019-04-01;13(1):9-13.

The p38/HOG stress-activated protein kinase network couples growth to division in Candida albicans.Sellam A, Chaillot J, Mallick J, Tebbji F, Richard Albert J, Cook MA, Tyers MPLoS Genet. 2019-03-28;15(3):e1008052.

Accurate quantitative proteomic analyses using metabolic labeling and High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS).Pfammatter S, Bonneil E, McManus FP, Thibault PJ. Proteome Res. 2019-03-28.

Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BLiScience 2019-03-15;14:47-57.

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