IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.



PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells.Kim SM, Nguyen TT, Ravi A, Kubiniok P, Finicle BT, Jayashankar V, Malacrida L, Hou J, Robertson J, Gao D, Chernoff J, Digman MA, Potma EO, Tromberg BJ, Thibault P, Edinger ALCancer Discov 2018-03-23.

PML requirement for interferon-induced global cellular SUMOylation.Maroui MA, Maarifi G, McManus FP, Lamoliatte F, Thibault P, Chelbi-Alix MKMol. Cell Proteomics 2018-03-13.

Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect.Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader SProc. Natl. Acad. Sci. U.S.A. 2018-03-13;115(11):E2653-E2662.

Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts using Two Isolation Methods.Lanoix J, Durette C, Courcelles M, Cossette É, Comtois-Marotte S, Hardy MP, Côté C, Perreault C, Thibault PProteomics 2018-03-06.

Understanding diversity in telomere dynamics.Monaghan P, Eisenberg DTA, Harrington L, Nussey DPhilos. Trans. R. Soc. Lond., B, Biol. Sci. 2018-03-05;373(1741).

In medio stat virtus: unanticipated consequences of telomere dysequilibrium.Harrington L, Pucci FPhilos. Trans. R. Soc. Lond., B, Biol. Sci. 2018-03-05;373(1741).

[Delivery in hypoxic tumor regions of a chemotherapeutic agent encapsulated in nanoliposomes carried by magnetoaerotactic bacteria].Felfoul O, Mohammadi M, Taherkhani S, Lanauze D, Zhong Xu Y, Lafleur M, Gaboury L, Tabrizian M, Vuong T, Batist G, Beauchemin N, Radzioch D, Martel SMed Sci (Paris) 2018-03-01;34(3):197-199.

Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin.Lavallée VP, Chagraoui J, MacRae T, Marquis M, Bonnefoy A, Krosl J, Lemieux S, Marinier A, Pabst C, Rivard GÉ, Hébert J, Sauvageau GLeukemia 2018-02-23.

MEK drives BRAF activation through allosteric control of KSR proteins.Lavoie H, Sahmi M, Maisonneuve P, Marullo SA, Thevakumaran N, Jin T, Kurinov I, Sicheri F, Therrien MNature 2018-02-22;554(7693):549-553.

CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein.Ouadda ABD, He Y, Calabrese V, Ishii H, Chidiac R, Gratton JP, Roux PP, Lamarche-Vane NOncotarget 2018-02-20;9(14):11646-11664.

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