IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia.Blood Cancer J 2018-07-19;8(8):68.
A TFEB nuclear export signal integrates amino acid supply and glucose availability.Nat Commun 2018-07-11;9(1):2685.
Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways.Proc. Natl. Acad. Sci. U.S.A. 2018-07-03;115(27):7051-7056.
Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.Trends Biochem. Sci. 2018-07-01;43(7):533-546.
PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells.Cancer Discov 2018-07-01;8(7):866-883.
Condensin ATPase motifs contribute differentially to the maintenance of chromosome morphology and genome stability.PLoS Biol. 2018-06-27;16(6):e2003980.
Backbone assignment of the apo-form of the human C-terminal domain of UDP-glucuronosyltransferase 1A (UGT1A).Biomol NMR Assign 2018-06-22.