IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.



Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways.Young M, Dahoun T, Sokrat B, Arber C, Chen KM, Bouvier M, Barth PProc. Natl. Acad. Sci. U.S.A. 2018-07-03;115(27):7051-7056.

Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AKTrends Biochem. Sci. 2018-07-01;43(7):533-546.

PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells.Kim SM, Nguyen TT, Ravi A, Kubiniok P, Finicle BT, Jayashankar V, Malacrida L, Hou J, Robertson J, Gao D, Chernoff J, Digman MA, Potma EO, Tromberg BJ, Thibault P, Edinger ALCancer Discov 2018-07-01;8(7):866-883.

Condensin ATPase motifs contribute differentially to the maintenance of chromosome morphology and genome stability.Palou R, Dhanaraman T, Marrakchi R, Pascariu M, Tyers M, D'Amours DPLoS Biol. 2018-06-27;16(6):e2003980.

Backbone assignment of the apo-form of the human C-terminal domain of UDP-glucuronosyltransferase 1A (UGT1A).Osborne MJ, Coutinho de Oliveira L, Volpon L, Borden KLBBiomol NMR Assign 2018-06-22.

Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo.Gerhold AR, Poupart V, Labbé JC, Maddox PSMol. Biol. Cell 2018-06-15;29(12):1435-1448.

Signaling Pathways Involved in the Regulation of mRNA Translation.Roux PP, Topisirovic IMol. Cell. Biol. 2018-06-15;38(12).

Meet the Editors: A career in Mass Spectrometry.Thibault PRapid Commun. Mass Spectrom. 2018-06-01.

Gas-Phase Enrichment of Multiply Charged Peptide Ions by Differential Ion Mobility Extend the Comprehensiveness of SUMO Proteome Analyses.Pfammatter S, Bonneil E, McManus FP, Thibault PJ. Am. Soc. Mass Spectrom. 2018-06-01;29(6):1111-1124.

Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin.Lavallée VP, Chagraoui J, MacRae T, Marquis M, Bonnefoy A, Krosl J, Lemieux S, Marinier A, Pabst C, Rivard GÉ, Hébert J, Sauvageau GLeukemia 2018-06-01;32(6):1349-1357.

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