Publications

IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.


2017

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SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism.Priam P, Krasteva V, Rousseau P, D'Angelo G, Gaboury L, Sauvageau G, Lessard JANat. Genet. 2017-05-01;49(5):753-764.

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca(2+) in Nonexcitable Cells.Stallaert W, van der Westhuizen ET, Schönegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier MMol. Pharmacol. 2017-05-01;91(5):533-544.

Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling.Gallion J, Koire A, Katsonis P, Schoenegge AM, Bouvier M, Lichtarge OHum. Mutat. 2017-05-01;38(5):569-580.

Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.Mathien S, Déléris P, Soulez M, Voisin L, Meloche SMol. Cell. Biol. 2017-05-01;37(9).

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme.Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Łach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B, Xiao Y, Xu X, Zhang D, Zok T, Westhof ERNA 2017-05-01;23(5):655-672.

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, Bouvier MNat Commun 2017-04-18;8:15054.

DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.Narbonne P, Maddox PS, Labbé JCPLoS Genet. 2017-04-14;13(4):e1006738.

EPCR expression marks UM171-expanded CD34(+) cord blood stem cells.Fares I, Chagraoui J, Lehnertz B, MacRae T, Mayotte N, Tomellini E, Aubert L, Roux PP, Sauvageau GBlood 2017-04-13.

Single-cell profiling reveals that eRNA accumulation at enhancer-promoter loops is not required to sustain transcription.Rahman S, Zorca CE, Traboulsi T, Noutahi E, Krause MR, Mader S, Zenklusen DNucleic Acids Res. 2017-04-07;45(6):3017-3030.

Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK.Kubiniok P, Lavoie H, Therrien M, Thibault PMol. Cell Proteomics 2017-04-01;16(4):663-679.

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