IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.Mol. Cell. Biol. 2017-12-15;37(24).
Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.Cell Rep 2017-11-28;21(9):2558-2570.
Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry.Nat Commun 2017-11-22;8(1):1701.
H3K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations.Blood 2017-11-16;130(20):2204-2214.
Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity.Clin. Cancer Res. 2017-11-15;23(22):6969-6981.
Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential.Front Pharmacol 2017-11-14;8:825.
Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.Brain Struct Funct 2017-11-06.
Identification of cross talk between SUMOylation and ubiquitylation using a sequential peptide immunopurification approach.Nat Protoc 2017-11-01;12(11):2342-2358.
Study of Methylene Blue Ototoxicity in the Guinea Pig.J Clin Med Res 2017-11-01;9(11):900-906.