Publications

IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.


2017

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Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.Pyakurel A, Balmer D, Saba-El-Leil MK, Kizilyaprak C, Daraspe J, Humbel BM, Voisin L, Le YZ, von Lintig J, Meloche S, Roduit RMol. Cell. Biol. 2017-12-15;37(24).

Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.St-Pierre C, Morgand E, Benhammadi M, Rouette A, Hardy MP, Gaboury L, Perreault CCell Rep 2017-11-28;21(9):2558-2570.

Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry.Kachaner D, Garrido D, Mehsen H, Normandin K, Lavoie H, Archambault VNat Commun 2017-11-22;8(1):1701.

H3K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations.Lehnertz B, Zhang YW, Boivin I, Mayotte N, Tomellini E, Chagraoui J, Lavallée VP, Hébert J, Sauvageau GBlood 2017-11-16;130(20):2204-2214.

Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity.Simon L, Lavallée VP, Bordeleau ME, Krosl J, Baccelli I, Boucher G, Lehnertz B, Chagraoui J, MacRae T, Ruel R, Chantigny Y, Lemieux S, Marinier A, Hébert J, Sauvageau GClin. Cancer Res. 2017-11-15;23(22):6969-6981.

Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential.Corrêa MF, Barbosa ÁJR, Teixeira LB, Duarte DA, Simões SC, Parreiras-E-Silva LT, Balbino AM, Landgraf RG, Bouvier M, Costa-Neto CM, Fernandes JPSFront Pharmacol 2017-11-14;8:825.

The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity.Zahreddine HA, Culjkovic-Kraljacic B, Emond A, Pettersson F, Midura R, Lauer M, Del Rincon S, Cali V, Assouline S, Miller WH, Hascall V, Borden KLElife 2017-11-07;6.

Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BLBrain Struct Funct 2017-11-06.

Identification of cross talk between SUMOylation and ubiquitylation using a sequential peptide immunopurification approach.McManus FP, Lamoliatte F, Thibault PNat Protoc 2017-11-01;12(11):2342-2358.

Study of Methylene Blue Ototoxicity in the Guinea Pig.Belhassen S, Alzahrani M, Nader ME, Gaboury L, Saliba IJ Clin Med Res 2017-11-01;9(11):900-906.

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