IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.



Understanding diversity in telomere dynamics.Monaghan P, Eisenberg DTA, Harrington L, Nussey DPhilos. Trans. R. Soc. Lond., B, Biol. Sci. 2018-03-05;373(1741).

In medio stat virtus: unanticipated consequences of telomere dysequilibrium.Harrington L, Pucci FPhilos. Trans. R. Soc. Lond., B, Biol. Sci. 2018-03-05;373(1741).

Cdc48/VCP Promotes Chromosome Morphogenesis by Releasing Condensin from Self-Entrapment in Chromatin.Thattikota Y, Tollis S, Palou R, Vinet J, Tyers M, D'Amours DMol. Cell 2018-02-15;69(4):664-676.e5.

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PPCancer Res. 2018-02-15.

MEK drives BRAF activation through allosteric control of KSR proteins.Lavoie H, Sahmi M, Maisonneuve P, Marullo SA, Thevakumaran N, Jin T, Kurinov I, Sicheri F, Therrien MNature 2018-02-12.

NUP98-BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy.Roussy M, Bilodeau M, Jouan L, Tibout P, Laramée L, Lemyre E, Cardin S, Sauvageau C, Couture F, Choblet A, Patey N, Gendron P, Duval M, Teira P, Hébert J, Wilhelm BT, Choi JK, Gruber TA, Bittencourt H, Cellot SGenes Chromosomes Cancer 2018-02-10.

Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 mRNA translation.Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, Schneider P, Hoang T, Allam RJ. Clin. Invest. 2018-02-06.

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia.Brown FC, Still E, Koche RP, Yim CY, Takao S, Cifani P, Reed C, Gunasekera S, Ficarro SB, Romanienko P, Mark W, McCarthy C, de Stanchina E, Gonen M, Seshan V, Bhola P, O'Donnell C, Spitzer B, Stutzke C, Lavallée VP, Hébert J, Krivstov AV, Melnick A, Paietta EM, Tallman MS, Letai A, Sauvageau G, Pouliot G, Levine R, Marto JA, Armstrong SA, Kentsis ACancer Discov 2018-02-05.

Ménière's Disease Pathophysiology: Endolymphatic Sac Immunohistochemical Study of Aquaporin-2, V2R Vasopressin Receptor, NKCC2, and TRPV4.Asmar MH, Gaboury L, Saliba IOtolaryngol Head Neck Surg 2018-02-01:194599818756829.

Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.Laumont CM, Perreault CCell. Mol. Life Sci. 2018-02-01;75(4):607-621.

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