Publications

Latest publications

  • July 7, 2022

    HMGA2 expression defines a subset of AML with immature transcriptional signature and vulnerability to G2/M inhibition.

    Moison C, Spinella JF, Chagraoui J, Lavallee VP, Lehnertz B, Thiollier C, Boivin I, Mayotte N, MacRae T, Marinier A, Hébert J, Sauvageau G
    Blood Adv 2022-07-07 ;.

  • July 2, 2022

    Michaelis-Menten quantification of ligand signalling bias applied to the promiscuous Vasopressin V2 receptor.

    Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D
    Mol Pharmacol 2022-07-02 ;.

  • July 1, 2022

    Community guidelines for GPCR ligand bias: IUPHAR review 32.

    Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov KA, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, Shukla AK, Sommer ME, Gloriam DE
    Br J Pharmacol 2022-07-01 ;179( 14 ):3651-3674.

  • July 1, 2022

    UM171 Expansion of Cord Blood Improves Donor Availability and HLA Matching For All Patients, Including Minorities.

    Dumont-Lagacé M, Feghaly A, Meunier MC, Finney M, Van't Hof W, Masson Frenet E, Sauvageau G, Cohen S
    Transplant Cell Ther 2022-07-01 ;28( 7 ):410.e1-410.e5.

  • June 28, 2022

    CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.

    Ansari U, Tomellini E, Chagraoui J, Lehnertz B, Mayotte N, Bordeleau ME, Roux PP, Sauvageau G
    Blood Adv 2022-06-28 ;6( 12 ):3626-3631.

  • June 26, 2022

    New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.

    Merali S, Wang Z, Frost C, Callejo M, Hedrick M, Hui L, Meadows Shropshire S, Xu K, Bouvier M, DeSouza MM, Yang J
    Platelets 2022-06-26 ;1-10.

  • June 21, 2022

    Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4.

    Priestley ES, Banville J, Deon D, Dubé L, Gagnon M, Guy J, Lapointe P, Lavallée JF, Martel A, Plamondon S, Rémillard R, Ruediger E, Tremblay F, Posy SL, Guarino VR, Richter JM, Li J, Gupta A, Vetrichelvan M, Balapragalathan TJ, Mathur A, Hua J, Callejo M, Guay J, Sum CS, Cvijic ME, Watson C, Wong P, Yang J, Bouvier M, Gordon DA, Wexler RR, Marinier A
    J Med Chem 2022-06-21 ;.

  • June 20, 2022

    Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells.

    Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, Lehnertz B, Sauvageau G, Manke T, Menendez P, Walter SG, Minguet S, Laurenti E, Günther S, Grün D, Cabezas-Wallscheid N
    Nat Cell Biol 2022-06-20 ;.

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