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Publication

Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complex.

Polo-like kinases control multiple events during cell division, including mitotic entry, centrosome organization, spindle formation, chromosome segregation and cytokinesis. Their roles during cytokinesis, however, are not well understood because the requirement of these kinases during early stages of mitosis complicates the study of their functions after anaphase onset.

Publication date
January 1, 2007
Principal Investigators
D'Avino PP, Archambault V, Przewloka MR, Zhang W, Lilley KS, Laue E, Glover DM
PubMed reference
PLoS ONE 2007;2(6):e572
PubMed ID
17593971
Affiliation
Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, United Kingdom. p.davino@gen.cam.ac.uk