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Publication — IRIC

YES, a novel therapeutic target in hepatocellular carcinoma.

Identification of dominant, actionable oncogenic signaling pathways is key to guide the development of new targeted treatments for advanced-stage hepatocellular carcinoma (HCC). We have recently unveiled a novel YES-YAP/TAZ signaling axis involved in liver cancer development. Our study identifies the tyrosine kinase YES as a potential therapeutic target in HCC.

Publication date
May 1, 2022
Principal Investigators
Lapouge M, Meloche S
PubMed reference
Mol Cell Oncol 2022;9(1):2069993
PubMed ID
Signaling and Cell Growth Laboratory, Institute for Research in Immunology and Cancer, Montreal, Quebec, Canada.