IRIC - Institute for Research in Immunology and Cancer

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112 results


Publications — IRIC November 6, 2022

CAXII Is a Surrogate Marker for Luminal Breast Tumors Regulated by ER and GATA3.

Porras L, Gorse F, Thiombane NK, Gaboury L, Mader S
Cancers (Basel) 2022-11-06 ;14( 21 ):.


Publications — IRIC August 29, 2022

Silicone particles in capsules around breast implants: Establishment of a new pathological methodology to assess the number of particles around breast implants.

Dziubek M, Laurent R, Bonapace-Potvin M, Gaboury L, Danino MA
Ann Chir Plast Esthet 2022-08-29 ;.


Publications — IRIC August 13, 2022

Combined IFN-γ and JAK inhibition to treat hemophagocytic lymphohistiocytosis in mice.

Joly JA, Vallée A, Bourdin B, Bourbonnais S, Patey N, Gaboury L, Théorêt Y, Decaluwe H
J Allergy Clin Immunol 2022-08-13 ;.


Publications — IRIC October 12, 2021

Impact of Epithelial-Mesenchymal Transition on the Immune Landscape in Breast Cancer.

Khadri FZ, Issac MSM, Gaboury L
Cancers (Basel) 2021-10-12 ;13( 20 ):.


Publications — IRIC September 15, 2021

Severe Inflammatory Reactions in Mice Expressing a GFI1P2A Mutant Defective in Binding to the Histone Demethylase KDM1A (LSD1).

Fraszczak J, Arman KM, Lacroix M, Vadnais C, Gaboury L, Möröy T
J Immunol 2021-09-15 ;207( 6 ):1599-1615.


Publications — IRIC March 1, 2021

The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis.

Blondel-Tepaz E, Leverve M, Sokrat B, Paradis JS, Kosic M, Saha K, Auffray C, Lima-Fernandes E, Zamborlini A, Poupon A, Gaboury L, Findlay J, Baillie GS, Enslen H, Bouvier M, Angers S, Marullo S, Scott MGH
Oncogene 2021-03-01 ;40( 12 ):2243-2257.


Publications — IRIC January 20, 2021

Survival Impact of Aggressive Treatment and PD-L1 Expression in Oligometastatic NSCLC.

Gauvin C, Krishnan V, Kaci I, Tran-Thanh D, Bédard K, Albadine R, Leduc C, Gaboury L, Blais N, Tehfe M, Routy B, Florescu M
Curr Oncol 2021-01-20 ;28( 1 ):593-605.


Publications — IRIC September 1, 2020

IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.

Benhammadi M, Mathé J, Dumont-Lagacé M, Kobayashi KS, Gaboury L, Brochu S, Perreault C
J. Immunol. 2020-09-01 ;205( 5 ):1268-1280.


Publications — IRIC July 24, 2020

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.

Aubert L, Nandagopal N, Steinhart Z, Lavoie G, Nourreddine S, Berman J, Saba-El-Leil MK, Papadopoli D, Lin S, Hart T, Macleod G, Topisirovic I, Gaboury L, Fahrni CJ, Schramek D, Meloche S, Angers S, Roux PP
Nat Commun 2020-07-24 ;11( 1 ):3701.


Publications — IRIC March 20, 2020

Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts.

Dieudé M, Turgeon J, Karakeussian Rimbaud A, Beillevaire D, Qi S, Patey N, Gaboury L, Boilard E, Hébert MJ
Am. J. Transplant. 2020-03-20 ;20( 3 ):726-738.


Publications — IRIC November 20, 2019

Axillary Lymph Node Ultrasound Following Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: Results from the SN FNAC Study.

Morency D, Dumitra S, Parvez E, Martel K, Basik M, Robidoux A, Poirier B, Holloway CMB, Gaboury L, Sideris L, Meterissian S, Boileau JF
Ann. Surg. Oncol. 2019-11-20 ;26( 13 ):4337-4345.


Publications — IRIC August 30, 2019

MCM2, MCM4, and MCM6 in Breast Cancer: Clinical Utility in Diagnosis and Prognosis.

Issac MSM, Yousef E, Tahir MR, Gaboury L
Neoplasia 2019-08-30 ;21( 10 ):1015-1035.


Publications — IRIC August 1, 2018

Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer.

El-Khoury V, Béland M, Schritz A, Kim SY, Nazarov PV, Gaboury L, Sertamo K, Bernardin F, Batutu R, Antunes L, Bennett CW, Faÿs F, Berchem G, Kim YJ
Br. J. Cancer 2018-08-01 ;119( 5 ):580-590.


Publications — IRIC May 1, 2018

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

Goyette MA, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault MP, Johnson RM, Carmeliet P, Basik M, Gaboury L, Muller WJ, Park M, Roux PP, Gratton JP, Côté JF
Cell Rep 2018-05-01 ;23( 5 ):1476-1490.


Publications — IRIC March 1, 2018

[Delivery in hypoxic tumor regions of a chemotherapeutic agent encapsulated in nanoliposomes carried by magnetoaerotactic bacteria].

Felfoul O, Mohammadi M, Taherkhani S, Lanauze D, Zhong Xu Y, Lafleur M, Gaboury L, Tabrizian M, Vuong T, Batist G, Beauchemin N, Radzioch D, Martel S
Med Sci (Paris) 2018-03-01 ;34( 3 ):197-199.


Publications — IRIC February 15, 2018

RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.

Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP
Cancer Res. 2018-02-15 ;.


Publications — IRIC February 1, 2018

Ménière’s Disease Pathophysiology: Endolymphatic Sac Immunohistochemical Study of Aquaporin-2, V2R Vasopressin Receptor, NKCC2, and TRPV4.

Asmar MH, Gaboury L, Saliba I
Otolaryngol Head Neck Surg 2018-02-01 ;194599818756829.


Publications — IRIC January 23, 2018

The E3 Ubiquitin Ligase HectD1 Suppresses EMT and Metastasis by Targeting the +TIP ACF7 for Degradation.

Duhamel S, Goyette MA, Thibault MP, Filion D, Gaboury L, Côté JF
Cell Rep 2018-01-23 ;22( 4 ):1016-1030.


Publications — IRIC November 28, 2017

Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.

St-Pierre C, Morgand E, Benhammadi M, Rouette A, Hardy MP, Gaboury L, Perreault C
Cell Rep 2017-11-28 ;21( 9 ):2558-2570.


Publications — IRIC November 1, 2017

PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.

Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP
Mol. Cancer Ther. 2017-11-01 ;16( 11 ):2528-2542.


Publications — IRIC November 1, 2017

Study of Methylene Blue Ototoxicity in the Guinea Pig.

Belhassen S, Alzahrani M, Nader ME, Gaboury L, Saliba I
J Clin Med Res 2017-11-01 ;9( 11 ):900-906.


Publications — IRIC September 19, 2017

HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma.

Matsuda H, Campion CG, Fujiwara K, Ikeda J, Cossette S, Verissimo T, Ogasawara M, Gaboury L, Saito K, Yamaguchi K, Takahashi S, Endo M, Fukuda N, Soma M, Hamet P, Tremblay J
Oncotarget 2017-09-19 ;8( 41 ):69559-69576.


Publications — IRIC May 22, 2017

Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis.

Williams V, Grosset AA, Zamorano Cuervo N, St-Pierre Y, Sylvestre MP, Gaboury L, Grandvaux N
BMC Cancer 2017-05-22 ;17( 1 ):356.


Publications — IRIC May 1, 2017

MCM2: An alternative to Ki-67 for measuring breast cancer cell proliferation.

Yousef EM, Furrer D, Laperriere DL, Tahir MR, Mader S, Diorio C, Gaboury L
Mod. Pathol. 2017-05-01 ;30( 5 ):682-697.


Publications — IRIC May 1, 2017

SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism.

Priam P, Krasteva V, Rousseau P, D'Angelo G, Gaboury L, Sauvageau G, Lessard J
Nat. Genet. 2017-05-01 ;49( 5 ):753-764.


Publications — IRIC November 30, 2016

Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer.

Grosset AA, Poirier F, Gaboury L, St-Pierre Y
PLoS ONE 2016-11-30 ;11( 11 ):e0166731.


Publications — IRIC November 1, 2016

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions.

Felfoul O, Mohammadi M, Taherkhani S, de Lanauze D, Zhong Xu Y, Loghin D, Essa S, Jancik S, Houle D, Lafleur M, Gaboury L, Tabrizian M, Kaou N, Atkin M, Vuong T, Batist G, Beauchemin N, Radzioch D, Martel S
Nat Nanotechnol 2016-11-01 ;11( 11 ):941-947.


Publications — IRIC September 1, 2016

First case report of an adrenocortical carcinoma caused by a BRCA2 mutation.

El Ghorayeb N, Grunenwald S, Nolet S, Primeau V, Côté S, Maugard CM, Lacroix A, Gaboury L, Bourdeau I
Medicine (Baltimore) 2016-09-01 ;95( 36 ):e4756.


Publications — IRIC April 5, 2016

Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets.

Grosset AA, Labrie M, Vladoiu MC, Yousef EM, Gaboury L, St-Pierre Y
Oncotarget 2016-04-05 ;7( 14 ):18183-203.


Publications — IRIC April 1, 2016

Cellular localisation of the kinin B1R in the pancreas of streptozotocin-treated rat and the anti-diabetic effect of the antagonist SSR240612.

Tidjane N, Gaboury L, Couture R
Biol. Chem. 2016-04-01 ;397( 4 ):323-36.


Publications — IRIC March 29, 2016

ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer.

Schlienger S, Campbell S, Pasquin S, Gaboury L, Claing A
Oncotarget 2016-03-29 ;7( 13 ):15811-27.


Publications — IRIC January 1, 2016

Placental Underperfusion in a Rat Model of Intrauterine Growth Restriction Induced by a Reduced Plasma Volume Expansion.

Bibeau K, Sicotte B, Béland M, Bhat M, Gaboury L, Couture R, St-Louis J, Brochu M
PLoS ONE 2016-01-01 ;11( 1 ):e0145982.


Publications — IRIC September 1, 2015

Stromal-Derived Factor-1α and Interleukin-7 Treatment Improves Homeostatic Proliferation of Naïve CD4(+) T Cells after Allogeneic Stem Cell Transplantation.

Gauthier SD, Leboeuf D, Manuguerra-Gagné R, Gaboury L, Guimond M
Biol. Blood Marrow Transplant. 2015-09-01 ;21( 9 ):1621-1632.


Publications — IRIC August 1, 2015

Frequency adaptation for enhanced radiation force amplitude in dynamic elastography.

Ouared A, Montagnon E, Kazemirad S, Gaboury L, Robidoux A, Cloutier G
IEEE Trans Ultrason Ferroelectr Freq Control 2015-08-01 ;62( 8 ):1453-66.


Publications — IRIC July 13, 2015

A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.

Labrie M, Vladoiu M, Leclerc BG, Grosset AA, Gaboury L, Stagg J, St-Pierre Y
PLoS ONE 2015-07-13 ;10( 7 ):e0131307.


Publications — IRIC June 23, 2015

The double capsules in macro-textured breast implants.

Giot JP, Paek LS, Nizard N, El-Diwany M, Gaboury L, Nelea M, Bou-Merhi JS, Harris PG, Danino MA
Biomaterials 2015-06-23 ;67:65-72.


Publications — IRIC June 1, 2015

The Added Value of Statistical Modeling of Backscatter Properties in the Management of Breast Lesions at US.

Trop I, Destrempes F, El Khoury M, Robidoux A, Gaboury L, Allard L, Chayer B, Cloutier G
Radiology 2015-06-01 ;275( 3 ):666-74.


Publications — IRIC April 1, 2015

A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes.

Tidjane N, Hachem A, Zaid Y, Merhi Y, Gaboury L, Girolami JP, Couture R
Eur J Inflamm 2015-04-01 ;13( 1 ):40-52.


Publications — IRIC January 20, 2015

Sentinel Node Biopsy After Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: The SN FNAC Study.

Boileau JF, Poirier B, Basik M, Holloway CM, Gaboury L, Sideris L, Meterissian S, Arnaout A, Brackstone M, McCready DR, Karp SE, Trop I, Lisbona A, Wright FC, Younan RJ, Provencher L, Patocskai E, Omeroglu A, Robidoux A
J. Clin. Oncol. 2015-01-20 ;33( 3 ):258-64.


Publications — IRIC December 1, 2014

Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.

Der Sarkissian S, Cailhier JF, Borie M, Stevens LM, Gaboury L, Mansour S, Hamet P, Noiseux N
Br. J. Pharmacol. 2014-12-01 ;171( 23 ):5265-79.


Publications — IRIC November 3, 2014

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells.

Grosset AA, Labrie M, Gagné D, Vladoiu MC, Gaboury L, Doucet N, St-Pierre Y
BMC Cancer 2014-11-03 ;14:801.


Publications — IRIC October 26, 2014

Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene.

Goupil M, Cousineau-Côté V, Aumont F, Sénéchal S, Gaboury L, Hanna Z, Jolicoeur P, de Repentigny L
BMC Immunol. 2014-10-26 ;15( 1 ):49.


Publications — IRIC September 15, 2014

Expression and functions of galectin-7 in ovarian cancer.

Labrie M, Vladoiu MC, Grosset AA, Gaboury L, St-Pierre Y
Oncotarget 2014-09-15 ;5( 17 ):7705-21.


Publications — IRIC September 2, 2014

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.

Shin EM, Sin Hay H, Lee MH, Goh JN, Tan TZ, Sen YP, Lim SW, Yousef EM, Ong HT, Thike AA, Kong X, Wu Z, Mendoz E, Sun W, Salto-Tellez M, Lim CT, Lobie PE, Lim YP, Yap CT, Zeng Q, Sethi G, Lee MB, Tan P, Goh BC, Miller LD, Thiery JP, Zhu T, Gaboury L, Tan PH, Hui KM, Yip GW, Miyamoto S, Kumar AP, Tergaonkar V
J. Clin. Invest. 2014-09-02 ;124( 9 ):3807-24.


Publications — IRIC August 23, 2014

MMP-9 expression varies according to molecular subtypes of breast cancer.

Yousef EM, Tahir MR, St-Pierre Y, Gaboury L
BMC Cancer 2014-08-23 ;14:609.


Publications — IRIC December 1, 2013

Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and Intralipid solutions and correlation to insulin levels.

d'Assignies G, Fontés G, Kauffmann C, Latour M, Gaboury L, Boulanger Y, Van Beers BE, Soulez G, Poitout V, Tang A
Metab. Clin. Exp. 2013-12-01 ;62( 12 ):1850-7.


Publications — IRIC April 1, 2013

Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene.

Leongson K, Cousineau-Côté V, Goupil M, Aumont F, Sénéchal S, Gaboury L, Jolicoeur P, Kronstad JW, de Repentigny L
Infect. Immun. 2013-04-01 ;81( 4 ):1100-13.


Publications — IRIC January 1, 2013

A rare case of large skull base meningioma mimicking otitis media with effusion.

Alzahrani M, Gaboury L, Saliba I
Case Rep Med 2013-01-01 ;2013:396805.


Publications — IRIC January 1, 2013

Expression and functions of galectin-7 in human and murine melanomas.

Biron-Pain K, Grosset AA, Poirier F, Gaboury L, St-Pierre Y
PLoS ONE 2013-01-01 ;8( 5 ):e63307.


Publications — IRIC November 1, 2012

Adoptive transfer of mesenchymal stromal cells accelerates intestinal epithelium recovery of irradiated mice in an interleukin-6-dependent manner.

François M, Birman E, Forner KA, Gaboury L, Galipeau J
Cytotherapy 2012-11-01 ;14( 10 ):1164-70.

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Louis Gaboury
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