92 results
The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens.
Vallet A, El Ezzy M, Diennet M, Haidar S, Bouvier M, Mader S
J Biol Chem
2022-11-29
;102757.
CAXII Is a Surrogate Marker for Luminal Breast Tumors Regulated by ER and GATA3.
Porras L, Gorse F, Thiombane NK, Gaboury L, Mader S
Cancers (Basel)
2022-11-06
;14(
21
):.
Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells.
Hosfield DJ, Weber S, Li NS, Suavage M, Joiner CF, Hancock GR, Sullivan EA, Nduwke E, Han R, Cush S, Lainé M, Mader S, Greene GL, Fanning SW
Elife
2022-05-16
;11;e72512:.
Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat.
Barrett RRG, Nash C, Diennet M, Cotnoir-White D, Doyle C, Mader S, Thomson AA, Gleason JL
Bioorg Med Chem Lett
2021-11-09
;55:128441.
Positive Regulation of Estrogen Receptor Alpha in Breast Tumorigenesis.
Porras L, Ismail H, Mader S
Cells
2021-10-31
;10(
11
):.
Minireview: what is known about SUMOylation among NR4A family members?
Dodat F, Mader S, Lévesque D
J Mol Biol
2021-08-23
;167212.
From Micro to Long: Non-Coding RNAs in Tamoxifen Resistance of Breast Cancer Cells.
Barazetti JF, Jucoski TS, Carvalho TM, Veiga RN, Kohler AF, Baig J, Al Bizri H, Gradia DF, Mader S, Carvalho de Oliveira J
Cancers (Basel)
2021-07-22
;13(
15
):.
Complex regulation of orphan nuclear receptor Nur77 (Nr4a1) transcriptional activity by SUMO2 and PIASγ.
Dodat F, Cotnoir-White D, Dianati E, Vallet A, Mader S, Lévesque D
Biochim Biophys Acta Mol Cell Res
2020-11-13
;1868(
2
):118908.
Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells.
Ghanbari F, Mader S, Philip A
Cells
2020-07-23
;9(
8
):.
Isolation and functional characterization of a novel endogenous inverse agonist of estrogen related receptors (ERRs) from human pregnancy urine.
Ghanbari F, Hebert-Losier A, Barry J, Poirier D, Giguere V, Mader S, Philip A
J. Steroid Biochem. Mol. Biol.
2019-04-05
;191:105352.
Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells.
Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader S
Oncogene
2019-02-01
;38(
7
):1019-1037.
Incorporation of histone deacetylase inhibitory activity into the core of tamoxifen - A new hybrid design paradigm.
Palermo AF, Diennet M, El Ezzy M, Williams BM, Cotnoir-White D, Mader S, Gleason JL
Bioorg. Med. Chem.
2018-08-15
;26(
15
):4428-4440.
Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect.
Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader S
Proc. Natl. Acad. Sci. U.S.A.
2018-03-13
;115(
11
):E2653-E2662.
MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets.
Lemieux S, Sargeant T, Laperrière D, Ismail H, Boucher G, Rozendaal M, Lavallée VP, Ashton-Beaucage D, Wilhelm B, Hébert J, Hilton DJ, Mader S, Sauvageau G
Nucleic Acids Res.
2017-07-27
;45(
13
):e122.
MCM2: An alternative to Ki-67 for measuring breast cancer cell proliferation.
Yousef EM, Furrer D, Laperriere DL, Tahir MR, Mader S, Diorio C, Gaboury L
Mod. Pathol.
2017-05-01
;30(
5
):682-697.
Single-cell profiling reveals that eRNA accumulation at enhancer-promoter loops is not required to sustain transcription.
Rahman S, Zorca CE, Traboulsi T, Noutahi E, Krause MR, Mader S, Zenklusen D
Nucleic Acids Res.
2017-04-07
;45(
6
):3017-3030.
Antiestrogens: structure-activity relationships and use in breast cancer treatment.
Traboulsi T, El Ezzy M, Gleason JL, Mader S
J. Mol. Endocrinol.
2017-01-01
;58(
1
):R15-R31.
Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection.
Bouttier M, Laperriere D, Memari B, Mangiapane J, Fiore A, Mitchell E, Verway M, Behr MA, Sladek R, Barreiro LB, Mader S, White JH
Nucleic Acids Res.
2016-12-15
;44(
22
):10571-10587.
MHC class I-associated peptides derive from selective regions of the human genome.
Pearson H, Daouda T, Granados DP, Durette C, Bonneil E, Courcelles M, Rodenbrock A, Laverdure JP, Côté C, Mader S, Lemieux S, Thibault P, Perreault C
J. Clin. Invest.
2016-12-01
;126(
12
):4690-4701.
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.
Mendoza-Sanchez R, Cotnoir-White D, Kulpa J, Jutras I, Pottel J, Moitessier N, Mader S, Gleason JL
Bioorg. Med. Chem.
2015-12-15
;23(
24
):7597-606.
The Estrogen Receptor Cofactor SPEN Functions as a Tumor Suppressor and Candidate Biomarker of Drug Responsiveness in Hormone-Dependent Breast Cancers.
Légaré S, Cavallone L, Mamo A, Chabot C, Sirois I, Magliocco A, Klimowicz A, Tonin PN, Buchanan M, Keilty D, Hassan S, Laperrière D, Mader S, Aleynikova O, Basik M
Cancer Res.
2015-10-15
;75(
20
):4351-63.
Selective ligand activity at Nur/retinoid X receptor complexes revealed by dimer-specific bioluminescence resonance energy transfer-based sensors.
Giner XC, Cotnoir-White D, Mader S, Lévesque D
FASEB J.
2015-10-01
;29(
10
):4256-67.
MicroRNAs Expression in Triple Negative vs Non Triple Negative Breast Cancer in Tunisia: Interaction with Clinical Outcome.
Medimegh I, Omrane I, Privat M, Uhrhummer N, Ayari H, Belaiba F, Benayed F, Benromdhan K, Mader S, Bignon IJ, Elgaaied AB
PLoS ONE
2014-11-04
;9(
11
):e111877.
Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases’ occurrence.
Medimegh I, Troudi W, Stambouli N, Khodjet-El-Khil H, Baroudi O, Ayari H, Omrane I, Uhrhammer N, Privat M, Mezlini A, Ayed FB, Romdhane KB, Mader S, Bignon YJ, Elgaaied AB
Med. Oncol.
2014-11-01
;31(
11
):255.
LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.
Bouchekioua-Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, Bachelot T, Chabaud S, Mader S, Dayan G, Treilleux I, Corbo L, Le Romancer M
Int. J. Cancer
2014-09-15
;135(
6
):1307-18.
Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1.
Calderon MR, Verway M, Benslama RO, Birlea M, Bouttier M, Dimitrov V, Mader S, White JH
Nucleic Acids Res.
2014-07-01
;42(
11
):7012-27.
Role of SUMOylation in full antiestrogenicity.
Hilmi K, Hussein N, Mendoza-Sanchez R, El-Ezzy M, Ismail H, Durette C, Bail M, Rozendaal MJ, Bouvier M, Thibault P, Gleason JL, Mader S
Mol. Cell. Biol.
2012-10-01
;32(
19
):3823-37.
The Transcription Factor Encyclopedia.
Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli M, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperriere D, Leprince D, de Cristofaro T, Prince KL, Putker M, Del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner N, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, Lebrun DP, Biswal S, Harvey CJ, Debruyne JP, Hogenesch JB, Hevner RF, Heligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW
Genome Biol
2012-03-29
;13(
3
):R24.
A prospective pilot study investigating the musculoskeletal pain in postmenopausal breast cancer patients receiving aromatase inhibitor therapy.
Robidoux A, Rich E, Bureau NJ, Mader S, Laperrière D, Bail M, Tremblay N, Patenaude M, Turgeon J
Curr Oncol
2011-12-01
;18(
6
):285-94.
Evolution of the repertoire of nuclear receptor binding sites in genomes.
Cotnoir-White D, Laperrière D, Mader S
Mol. Cell. Endocrinol.
2011-03-01
;334(
1-2
):76-82.
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.
de Verteuil D, Muratore-Schroeder TL, Granados DP, Fortier MH, Hardy MP, Bramoullé A, Caron E, Vincent K, Mader S, Lemieux S, Thibault P, Perreault C
Mol. Cell Proteomics
2010-09-01
;9(
9
):2034-47.
Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin beta2 innate immune pathway defective in Crohn disease.
Wang TT, Dabbas B, Laperriere D, Bitton AJ, Soualhine H, Tavera-Mendoza LE, Dionne S, Servant MJ, Bitton A, Seidman EG, Mader S, Behr MA, White JH
J. Biol. Chem.
2010-01-22
;285(
4
):2227-31.
Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates.
Sima A, Parisotto M, Mader S, Bhat PV
Biochim. Biophys. Acta
2009-12-01
;1790(
12
):1660-4.
Function of histone deacetylase 6 as a cofactor of nuclear receptor coregulator LCoR.
Palijan A, Fernandes I, Bastien Y, Tang L, Verway M, Kourelis M, Tavera-Mendoza LE, Li Z, Bourdeau V, Mader S, Yang XJ, White JH
J. Biol. Chem.
2009-10-30
;284(
44
):30264-74.
Ligand-dependent corepressor LCoR is an attenuator of progesterone-regulated gene expression.
Palijan A, Fernandes I, Verway M, Kourelis M, Bastien Y, Tavera-Mendoza LE, Sacheli A, Bourdeau V, Mader S, White JH
J. Biol. Chem.
2009-10-30
;284(
44
):30275-87.
NF-kappaB and estrogen receptor alpha interactions: Differential function in estrogen receptor-negative and -positive hormone-independent breast cancer cells.
Gionet N, Jansson D, Mader S, Pratt MA
J. Cell. Biochem.
2009-06-01
;107(
3
):448-59.
Fast-tracking steroid receptor crystallization.
Mader S
Nat. Chem. Biol.
2008-04-01
;4(
4
):226-7.
Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells.
Bourdeau V, Deschênes J, Laperrière D, Aid M, White JH, Mader S
Nucleic Acids Res.
2008-01-01
;36(
1
):76-93.
Isomer-specific retinoic acid biosynthesis in HeLa cells expressing recombinant class I aldehyde dehydrogenases.
Brodeur H, Parisotto M, Chagnon S, Mader S, Bhat PV
Biochim. Biophys. Acta
2007-11-01
;1770(
11
):1548-56.
A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum.
Quignodon L, Grijota-Martinez C, Compe E, Guyot R, Allioli N, Laperrière D, Walker R, Meltzer P, Mader S, Samarut J, Flamant F
J. Mol. Endocrinol.
2007-07-01
;39(
1
):17-28.
Regulation of GREB1 transcription by estrogen receptor alpha through a multipartite enhancer spread over 20 kb of upstream flanking sequences.
Deschênes J, Bourdeau V, White JH, Mader S
J. Biol. Chem.
2007-06-15
;282(
24
):17335-9.
Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12.
Lupien M, Jeyakumar M, Hébert E, Hilmi K, Cotnoir-White D, Loch C, Auger A, Dayan G, Pinard GA, Wurtz JM, Moras D, Katzenellenbogen J, Mader S
Mol. Endocrinol.
2007-04-01
;21(
4
):797-816.
Rational design of an estrogen receptor mutant with altered DNA-binding specificity.
Nguyen D, Bail M, Pesant G, Dupont VN, Rouault E, Deschênes J, Rocha W, Melançon G, Steinberg SV, Mader S
Nucleic Acids Res.
2007-01-01
;35(
10
):3465-77.
Widespread Alu repeat-driven expansion of consensus DR2 retinoic acid response elements during primate evolution.
Laperriere D, Wang TT, White JH, Mader S
BMC Genomics
2007-01-01
;8:23.
[Retinoid metabolism and cancer]
Parisotto M, Brodeur H, Bhat PV, Mader S
Med Sci (Paris)
2006-12-01
;22(
12
):1101-6.
Kinetic properties of chimeric class I aldehyde dehydrogenases for retinal isomers.
Brodeur H, Chagnon S, Parisotto M, Mader S, Bhat PV
Biochem. Cell Biol.
2006-10-01
;84(
5
):799-804.
Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor alpha.
Dayan G, Lupien M, Auger A, Anghel SI, Rocha W, Croisetière S, Katzenellenbogen JA, Mader S
Mol. Pharmacol.
2006-08-01
;70(
2
):579-88.
Convergence of vitamin D and retinoic acid signalling at a common hormone response element.
Tavera-Mendoza L, Wang TT, Lallemant B, Zhang R, Nagai Y, Bourdeau V, Ramirez-Calderon M, Desbarats J, Mader S, White JH
EMBO Rep.
2006-02-01
;7(
2
):180-5.
Antimony trioxide-induced apoptosis is dependent on SEK1/JNK signaling.
Mann KK, Davison K, Colombo M, Colosimo AL, Diaz Z, Padovani AM, Guo Q, Scrivens PJ, Gao W, Mader S, Miller WH
Toxicol. Lett.
2006-01-05
;160(
2
):158-70.
Genome-wide approaches for identification of nuclear receptor target genes.
Tavera-Mendoza LE, Mader S, White JH
2006-01-01
;4:e018.