Publication — IRIC

Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells.

Resistance to apoptosis induced by anti-cancer drugs is a major obstacle for the treatment of aggressive forms of breast cancer. Galectin-7 (gal-7) was recently shown to be specifically expressed in basal-like but not in luminal subtypes of human breast cancer.

Date de publication
3 novembre 2014
Chercheurs
Grosset AA, Labrie M, Gagné D, Vladoiu MC, Gaboury L, Doucet N, St-Pierre Y
Référence PubMed
BMC Cancer 2014;14:801
ID PubMed
25367122
Affiliation
INRS-Institut Armand-Frappier, 531 Blv, des Prairies, Laval, Quebec H7V 1B7, Canada. yves.st-pierre@iaf.inrs.ca.