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2012-2013 Activity Report - Making History: Ten Years of impact  > More

World breakthrough: a new molecule allows for an increase in stem cell transplants  > More


  • October 1, 2014 10:00IRIC on the road: University of British Columbia - 2014 Graduate and Professional Schools Fair
  • October 2, 2014 11:00IRIC on the road: University of Toronto (St. George) - 2014 Graduate and Professional Schools Fair
  • October 2, 2014 11:30Membrane Proteomics: Surface Markers & Horizontal Signaling
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Recent Publications

Dimerization-induced allostery in protein kinase regulation.Lavoie H et al.Trends Biochem. Sci. 2014. > More

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.Fares I et al.Science 2014. > More

The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival.Marquis M et al.Mol. Cell. Biol. 2014. > More

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.Bouchekioua-Bouzaghou K et al.Int. J. Cancer 2014. > More

Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.Blanchet MF et al.Nucleic Acids Res. 2014. > More

Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS.Beautrait A et al.J. Biol. Chem. 2014. > More

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.Bordeleau ME et al.Blood 2014. > More

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.Shin EM et al.J. Clin. Invest. 2014. > More

When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage.Serrano D et al.Syst Synth Biol 2014. > More

Biased Signaling Favoring Gi over β-Arrestin Promoted by an Apelin Fragment Lacking the C-terminal Phenylalanine.Ceraudo E et al.J. Biol. Chem. 2014. > More

KIF14 Binds Tightly to Microtubules and Adopts a Rigor-Like Conformation.Arora K et al.J. Mol. Biol. 2014. > More