Research

Accelerating the discovery of new, more effective therapies to treat cancer > More

Students

An ultra-modern training centre for the next generation of scientists at the heart of Université de Montréal > More

Support IRIC

Multiple opportunities to participate in our discoveries > More

News

IRIC Great Challenges Against Cancer raises a record amount of $415,000  > More

Calendar

  • November 3, 2014 11:30Controlling Phosphatases Through Unfair Competition
  • November 5, 2014 10:00IRIC on the road: McGill University - 2014 Graduate Schools Fair (SUS)
  • November 7, 2014 10:30BIM 6070 Lecture: « Is it (really!) better to give than to receive? A scientist journey in the granting world »
AEC v1.0.4

Recent Publications

Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases' occurrence.Medimegh I et al.Med. Oncol. 2014. > More

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.Bordeleau ME et al.Blood 2014. > More

Structural Maintenance of Chromosome (SMC) Proteins Link Microtubule Stability to Genome Integrity.Laflamme G et al.J. Biol. Chem. 2014. > More

Dimerization-induced allostery in protein kinase regulation.Lavoie H et al.Trends Biochem. Sci. 2014. > More

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin.Armando S et al.FASEB J. 2014. > More

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.Fares I et al.Science 2014. > More

Expression and functions of galectin-7 in ovarian cancer.Labrie M et al.Oncotarget 2014. > More

The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival.Marquis M et al.Mol. Cell. Biol. 2014. > More

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.Bouchekioua-Bouzaghou K et al.Int. J. Cancer 2014. > More

Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.Blanchet MF et al.Nucleic Acids Res. 2014. > More

Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS.Beautrait A et al.J. Biol. Chem. 2014. > More