Research

Accelerating the discovery of new, more effective therapies to treat cancer > More

Students

An ultra-modern training centre for the next generation of scientists at the heart of Université de Montréal > More

Support IRIC

Multiple opportunities to participate in our discoveries > More

Calendar

  • June 1, 2016 09:00Molecular genetics of cancer
  • June 2, 2016The Cell Cycle: from Mechanisms to Therapy - IRIC 10th International Symposium
  • June 6, 2016 09:00How to write a grant
AEC v1.0.4

Recent Publications

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.Volpon L et al.Proc. Natl. Acad. Sci. U.S.A. 2016. > More

Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.Duhamel S et al.Cell Cycle 2016. > More

Structural and Transcriptomic Response to Antenatal Corticosteroids in an Erk3-null Mouse Model of Respiratory Distress.Pew BK et al.Am. J. Obstet. Gynecol. 2016. > More

Data Independent Acquisition analysis in ProHits 4.0.Liu G et al.J Proteomics 2016. > More

Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.Rentas S et al.Nature 2016. > More

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines that Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.Fraser C et al.J. Med. Chem. 2016. > More

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.Pabst C et al.Blood 2016. > More

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction.Bradley SJ et al.Proc. Natl. Acad. Sci. U.S.A. 2016. > More

ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential.Frémin C et al.Oncogene 2016. > More

Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress.Simoneau A et al.Nucleic Acids Research 2016. > More

Econazole Imprinted Textiles with Antifungal ActivityHossain MA et al.Eur. J. Pharmacol. 2016. > More