A unique model
IRIC, located in the heart of the Université de Montréal campus, operates according to a unique model in Canada that combines, under one roof, fundamental research activities, a university-level training program and a research maturation team. These generate discoveries that advance knowledge or that can quickly translate into new therapeutic solutions.
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News Sébastien Carréno collaborates with a team from France on a study published in EMBO J
Sébastien Carréno, Director of IRIC’s Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility Research Unit, has signed a new publication in EMBO J with colleagues from the Institute of Pharmacology and Structural Biology of Toulouse. The project was led by PhD student Perrine Verdys, co-supervised by Professor Carréno. The group’s work demonstrates that macrophages, which are immune cells, can migrate without the ERM proteins, cell cortex proteins until now considered essential to any cell migration process.
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News Three IRIC projects funded by the Canadian Institutes of Health Research
The Canadian Institutes of Health Research (CIHR) recently awarded Project Grants for the Spring 2024 competition. This program aims to support original ideas with the potential to advance basic and applied health knowledge. Across the country, 373 research projects, representing a total investment of $325 million, have been funded. Three IRIC projects are recipients of these prestigious grants.
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News 2024 Student Recruitment Event: meeting a new generation of motivated and diversified students
The 2024 edition took place from June 5 to 7 and welcomed 32 participants from universities around the world. More than 150 interviews were scheduled this year between participants and the Institute researchers present at the event.
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News Targeting the surface of leukemia cells with immunotherapies
Immunotherapies, which are more natural and less toxic than chemotherapies, have made major advances in recent years. However, they remain relatively unexploited in the treatment of acute myeloid leukemia (AML), a type of leukemia that is particularly heterogeneous genetically and difficult to treat. The Leucegene group, led by Guy Sauvageau (IRIC’s Molecular Genetics of Stem Cells Research Unit) and Josée Hébert (Centre de recherche de l’Hôpital Maisonneuve-Rosemont), and involving the teams of Philippe Roux, Sébastien Lemieux and Pierre Thibault at IRIC, and of Vincent-Philippe Lavallée at the CHU Ste-Justine Research Centre, has developed a new approach to analyze the molecules present on the surface of leukemia cells. Their work has led to the identification, in AML specimens, of new high-potential targets for immunotherapies. The study was led by Marie-Ève Bordeleau, Deputy Director of the Sauvageau laboratory, and is published in the journal Cell Reports.
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News Marc Therrien takes the position of Interim Chief Executive Officer of IRIC
IRIC is pleased to announce the appointment of Professor Marc Therrien as Interim Chief Executive Officer of IRIC. The Executive Council of the Université de Montréal recently ratified the recommendation made by IRIC’s Board of Directors. Marc Therrien is Principal Investigator in the Institute’s Intracellular Signalling Research Unit and Full Professor in the Department of Pathology and Cell Biology at the Faculty of Medicine of the Université de Montréal.
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Event Run for the cause or support Équipe IRIC at the 2024 Montreal Beneva Marathon!
21—22 September, 2024
The 32nd edition of the Montreal Beneva Marathon will be held on September 21 and 22. Donations collected by the IRIC team help fund the Institute’s cancer research and student scholarships.
Upcoming events
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February 15, 2024—August 31, 2025 Université de Montréal launches “L’heure est brave” campaign
To meet the major challenges of our time, the Université de Montréal is launching the “L’heure est brave” campaign. By contributing, you will help the University to develop the potential of its students, innovate for the common good, look after the health of living beings and improve the daily lives of communities. Your donations can make a difference. Let’s join forces to build tomorrow’s world.
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Upcoming 21—22 September, 2024
Latest publications
See all publications-
July 18, 2024 Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics.
Verdys P, Rey Barroso J, Girel A, Vermeil J, Bergert M, Sanchez T, Métais A, Mangeat T, Bellard E, Bigot C, Astarie-Dequeker C, Labrousse A, Girard JP, Maridonneau-Parini I, Vérollet C, Lagarrigue F, Diz-Muñoz A, Heuvingh J, Piel M, du Roure O, Le Cabec V, Carréno S, Poincloux R
EMBO J 2024-07-18 ; - See all publications