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Publications

Latest publications

  • May 28, 2026

    LRRK2 mutations block NCOA4 trafficking upon iron overload leading to ferroptotic death.

    Goldman A, Nguyen M, Lanoix J, Li C, Fahmy A, Xu YZ, Schurr E, Thibault P, Desjardins M, McBride HM
    J Cell Sci 2026-05-28 ;

  • May 15, 2026

    TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition.

    Spinella JF, Chagraoui J, Moison C, Boivin I, Carpentier GR, Mayotte N, Béliveau F, Lavallée VP, Hébert J, Sauvageau G
    Sci Adv 2026-05-15 ;12( 20 ):eaed7122

  • May 15, 2026

    The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

    Lefrançois G, Lavallée E, Rowell MC, Bourdeau V, Mohebali F, Bertomeu T, Duman AM, Nikolova M, Tyers M, Gravel SP, Schmitzer AR, Ferbeyre G
    Elife 2026-05-15 ;13:

  • May 8, 2026

    Neutrophil-targeted liposomal inhibition of PAD4-mediated NETosis in systemic lupus erythematosus.

    Rezaei N, Ménard L, Moawad F, Marazzi G, Stepanov A, Peqini K, Trinh VQ, Pellegrino S, Marleau S, Brambilla D
    J Control Release 2026-05-08 ;115006

  • May 7, 2026

    Non-canonical transcription and splicing shape the colorectal cancer immunopeptidome in MSI and MSS tumors.

    Courcelles M, Hardy MP, Durette C, Lanoix J, Minati R, Laverdure JP, Vincent K, Perreault C, Thibault P
    Mol Cell Proteomics 2026-05-07 ;101581

  • May 7, 2026

    Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long-chain fatty acid accumulation after myocardial ischemia-reperfusion in mice.

    Gauvin J, Radmannia N, Huynh DN, Ménard L, Daneault C, Veilleux M, Ahsanullah A, Carpentier AC, Lubell WD, Ruiz M, Ong H, Marleau S, Gravel SP
    FEBS Open Bio 2026-05-07 ;

  • April 29, 2026

    Selective Nanobody-Derived Minibodies Targeting Galectin-1 and -7 Reveal Non-Redundant Glyco-Immune Functions and Therapeutic Potential in Triple-Negative Breast Cancer.

    Nehmé R, Fortier M, Granger Joly de Boissel P, Caza F, Fronton F, Bourguignon L, Charpentier T, Fuselier C, Ferchiou S, D'Auteuil N, Gaboury L, Lamarre A, Chatenet D, St-Pierre Y
    J Med Chem 2026-04-29 ;

  • April 13, 2026

    Targeting the H/KRAS α4-β6-α5 Allosteric Lobe with Macrocyclic Peptides.

    Tran K, Lavoie H, Wahhab A, Garrido D, Jo CH, Poupart MA, Arya T, Beautrait A, Killoran R, Dicaire-Leduc C, Bonneil E, Osborne M, Schuetz DA, Shaikh F, Thibault P, Smith M, Marinier A, Therrien M
    ACS Med Chem Lett 2026-04-13 ;17( 5 ):1154-1162

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