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Publications

Latest publications

  • August 31, 2026

    Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC.

    Saatci O, Ulukan B, Cetin M, Kuasne H, Martinez C, Percin E, Oleinik N, Savoca MT, Nehme A, Hernández-Corchado A, Zavacky E, Sreenivas K, Rezaeian AH, Bethard JR, Anoma JS, Sahin OS, Aguilar-Mahecha A, Buchanan M, Aras M, DeBlois G, Basik M, Hill EG, Ball LE, Rao CN, McInnes C, Riazalhosseini Y, Najafabadi HS, Lemasters JJ, Ogretmen B, Park M, Sahin O
    Cell Rep Med 2026-08-31 ;7( 9 ):103015

  • August 28, 2026

    The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology.

    Hadas Yardeni E, Kiss DJ, Sanchez J, Shavit K, Szepesi Kovács D, Egyed A, Vogt CD, Gaitonde SA, Glenn J, Canals M, Bouvier M, Newman AH, Lane JR, Keserű GM, Shalev-Benami M
    Sci Adv 2026-08-28 ;12( 35 ):eaef7411

  • August 18, 2026

    Modeling KRAS mutations in KMT2A::MLLT3 acute myeloid leukemia promotes leukemic progression and transcriptional rewiring.

    Esparza N, Defrêne J, Bresson E, Soufflet AC, Juárez-Rodríguez MM, Lisi V, Hernández-Sánchez A, Bullinger L, Lavallée VP, Wilhelm B, Barabé F
    Leukemia 2026-08-18 ;

  • August 5, 2026

    A distinctive PDZ:β-hairpin interaction mediates AFDN complex with SCRIB and promotes binding to KRAS.

    Jo CH, Strakhova R, Goudreault M, Bernal Astrain G, Smith M
    Biochem J 2026-08-05 ;483( 8 ):1575-1589

  • August 4, 2026

    Invariant chain controls HLA-DQ folding and shapes the HLA class II proxiome.

    Moulefera MA, Mitchell W, Bilali NE, Majdoubi A, Panès R, Salti S, Lippé R, Gagnon E, Mourad W, Thibodeau J
    J Immunol 2026-08-04 ;215( 8 ):

  • July 31, 2026

    The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

    Goyette M, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault MP, Johnson RM, Carmeliet P, Basik M, Gaboury L, Muller WJ, Park M, Roux PP, Gratton JP, Côté JF
    Cell Rep 2026-07-31 ;45( 8 ):117807

  • July 22, 2026

    License to slice: duplex deformation gates Argonaute catalysis.

    Major F
    Nat Struct Mol Biol 2026-07-22 ;

  • July 21, 2026

    Expanding the Caenorhabditis elegans toolkit with gonad explants.

    Zellag RM, Cheng E, Gerhold AR, Labbé J
    Development 2026-07-21 ;153( 14 ):

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