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November 9, 2020 Sébastien Lemieux and his team’s project is a recipient of the ODAC Competition
Génome Québec, IVADO and Oncopole have come together to organize the “Omics Data Against Cancer” (ODAC) Competition. This initiative aims to support projects developing applications and artificial intelligence tools used to better exploit the datasets generated by genomics and the study of cancer.
The project of Sébastien Lemieux, Principal Investigator at IRIC and his team is one of the 5 recipient projects of the program.
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October 20, 2020 IRIC’s Academic Affairs team receives the prix d’excellence en enseignement
IRIC is proud to announce that the prix d’excellence en enseignement Catégorie Innovation – Soutien à la réussite étudiante has been awarded to its Academic Affairs team: Sébastien Carréno, Julie Mantovani, Evelyne Muhire, Pascale Le Thérizien. This recognition bestowed by the Vice-Rector of Student and Academic Affairs of the Université de Montréal underscores the outstanding contribution made by the team to student success.
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October 15, 2020 2020 student recruitment tour: a virtual edition this fall
Each fall, the IRIC’s Academic Affairs team launches an “IRIC on the road” student recruitment tour. This year, in the exceptional context caused by the COVID-19 pandemic, our representatives are going to meet students virtually. They will participate in several graduate studies fairs organized on the web by various Canadian universities.
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October 14, 2020 A donation benefiting IRIC and the Department of Biochemistry and Molecular Medicine of the UdeM
As part of a major planned donations campaign, led by the Réseau des diplômés et des donateurs de l’Université de Montréal, Michel Bouvier, Chief Executive Officer of IRIC and his partner, Muriel Aubry, announced their testamentary donation benefiting IRIC and the Department of Biochemistry and Molecular Medicine of the UdeM, in support of cancer research and the training of the next generation of scientists.
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October 13, 2020 Breaking the RNA capping paradigm
This discovery by a team of IRIC researchers could soon be taught in molecular biology courses. Katherine Borden’s laboratory recently published a study in the journal PNAS that demonstrated that the activity of RNAs can be regulated in a new way: by modulating a RNA modification known as capping.
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September 4, 2020 Three IRIC researchers receive substantial support from the Canada Foundation for Innovation
On August 18, 2020, the Canada Foundation for Innovation (CFI) announced the selected research projects that will benefit from its financial support. This substantial support allows researchers to acquire highly specialized avant-garde equipment and infrastructure, and to recruit and retain internationally renowned scientists.
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August 6, 2020 Genome-wide screens reveal that resveratrol induces replicative stress in human cells
Resveratrol (RSV) is a natural compound found in many plants, including the skin of grapes (and in wine), blueberries, raspberries, mulberries and peanuts. It has attracted considerable research attention due to its reported beneficial properties in experimental models such as yeasts, nematode worms, fruit flies and mice, including lifespan extension under certain conditions. A causal role of RSV in human health has not yet been established.
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November 12, 2020 -
November 12, 2020 -
October 14, 2020 Exploring uncharted territories in RAS signaling leads to many surprises
There are over 160 small GTPase proteins in human cells that can fluctuate between an active state (“on”) and an inactive state (“off”). These work as switches to control whether intracellular signaling pathways are turned on or off. Of particular interest are GTPases of the RAS family. Mutations in these GTPases are among the main causes of human cancers, yet there are currently no therapeutics targeting RAS proteins themselves.
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September 1, 2020 IRIC congratulates Dr. Patrick Cossette on being appointed Dean of the Faculty of Medicine
At its June 8 meeting, the Board of Directors of the Université de Montréal appointed Dr. Patrick Cossette Dean of the Faculty of Medicine for a term beginning today, September 1, 2020, and ending on May 31, 2025. IRIC would like to offer its heartfelt congratulations to Dr. Cossette and his team on the appointment and wishes them great success in their new duties.
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August 28, 2020 Fatéma Dodat, PhD student at IRIC and Faculté de Pharmacie, created a popular science blog to allow students to promote research
Lockdown and the pandemic caused multiple consequences among which an increase in screen time and more people looking for reliable scientific news. At the end of her PhD in Pharmaceutical Sciences and passionate about popularizing science, Fatéma Dodat took advantage of this period to develop a blog (https://www.point-science.com/) that promotes accessible scientific news.
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August 13, 2020 In memoriam - IRIC pays tribute to Dr. André Robidoux
It was with great sadness that IRIC learned of the death of André Robidoux, who passed away on July 25, surrounded by his family.
Renowned surgical oncologist, his body of work included being part of the National Surgical Adjuvant Breast and Bowel Project to promote clinical tests aimed at validating new therapies. Devoted to his patients, he also wanted to convey his knowledge to them.
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July 30, 2020 2020 IRIC Next Generation Awards Competition: a successful edition in the midst of a pandemic
As always, IRIC is actively involved in training the next generation of scientists. That’s why, since 2011, the Institute has made it possible for Canadian undergraduate students to carry out a summer internship in one of its laboratories as part of the IRIC Next Generation Awards Competition. This summer, however, the unique health context and teleworking have upended the training of these research interns.
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July 29, 2020 Targeting cell surface proteins and copper in the fight against colorectal cancer
In some cases, taking the direct path is not the most effective. A study led by the team of Philippe Roux, in collaboration with the teams of Louis Gaboury and Sylvain Meloche of IRIC, indeed reveals that the oncogenic protein KRAS could be targeted indirectly. Recently published in Nature Communications, their results demonstrate that mutation of this oncogene modifies the expression of proteins at the surface of the cells that cover the internal villi of the intestine. This study offers new therapeutic opportunities for the treatment of colorectal cancer.
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July 27, 2020 IRCM and IRIC researchers collaborate with the University of Cambridge to reveal a mechanism involved in the formation of metastases
In an article recently published in the prestigious journal Nature Communications, researchers from the Montreal Clinical Research Institute (IRCM) and the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal collaborated with eminent researcher David Barford of the University of Cambridge to shed light on the 3D structure of the ELMO / DOCK2 complex.
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July 22, 2020 The project carried out by Sylvie Mader and her team receives the LeadAction|Breast Cancer du Sein grant
While the pandemic has highlighted the importance of supporting scientific research, IRICoR and the Quebec Breast Cancer Foundation (QBCF) have joined forces through their joint LeadAction|Breast Cancer Competition to accelerate breast cancer research work and develop additional therapeutic options for those affected by this cancer.
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July 2, 2020 The lockdown related to COVID-19 severely affected early-career investigators and clinical trials
The research sectors particularly impacted by the pandemic are beginning to be identified. David Knapp, Principal Investigator at IRIC, in collaboration with David G. Kent (University of York) and Nagarajan Kannan (Mayo Clinic), highlight the consequences of the health crisis on early-career investigators and clinical trials. The analysis stems from data collected by a survey shared by the International Society for Stem Cell Research (ISSCR) among its members. Carried out between April 6 and April 15, 2020, 762 investigators from 52 countries responded. Here is a look back at this analysis published in Stem Cell Reports and on the main issues that were raised.
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June 30, 2020 -
June 23, 2020 IRIC is pleased to mark more than 10 years of partnership with Pomerleau and acknowledges its outstanding support
On June 1, 2020, Pomerleau, one of Canada’s most innovative construction leaders and a pioneer in sustainable buildings and renewable energy, launched its “Love is an essential service” initiative to support efforts to fight COVID-19. As part of that initiative, philanthropic donations were distributed to 14 community organizations across the country working in three major sectors of activity related to the current health crisis, namely: health, research and food. As a result, IRIC has been allocated a substantial amount, deposited into the Institute’s Emergency Fund, to allow its investigators to continue their research activities in a bold and unique way, despite the constraints stemming from the pandemic.
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June 17, 2020 Race for the discovery of COVID-19 medications: A multidisciplinary project takes shape!
Génome Québec, in partnership with IRIC, Université de Montréal, Mila – Quebec Artificial Intelligence Institute and McMaster University, is proud to announce funding for a new research project intended to accelerate the discovery of antiviral COVID-19 medications. Spearheaded by professors Michael Tyers (IRIC / Université de Montréal), Yoshua Bengio (Mila / Université de Montréal) and Anne Marinier (IRIC / Université de Montréal), the $1 million project was launched in fast-track mode on June 1, 2020.
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June 10, 2020 IRIC thanks Mr. Sauvé for his testamentary donation
IRIC is very grateful to announce the philanthropic support of donor Pierre Sauvé, Engr., a 1966 graduate of Polytechnique Montréal. Extensively involved with the Université de Montréal over the past few years, particularly with l’Association des diplômés, Mr. Sauvé has shown tremendous generosity towards our academic institution on many occasions.
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June 5, 2020 IRIC is delighted by the renewed funding from the Richard and Edith Strauss Foundation in support of cancer research
IRIC would like to offer its heartfelt thanks for the commitment made by the Richard and Edith Strauss Foundation, which is renewing its support for 2 promising cancer research projects.
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June 4, 2020 IRIC broadens its ranks by recruiting David Knapp and Geneviève Deblois as new Principal Investigators
The Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal is proud to announce that David Knapp and Geneviève Deblois have been recruited as new Principal Investigators. They are in charge, respectively, of the Cellular Engineering Research Unit and the Metabolic and Epigenetic Alterations in Cancer Research Unit.