RECHERCHE

Pôle de recherche pour accélérer la découverte de thérapies plus efficaces contre le cancer > Plus

ÉTUDIANTS

Un centre de formation ultra-moderne pour la relève scientifique au coeur de l'Université de Montréal > Plus

APPUYER L'IRIC

De nombreuses occasions de participer à nos découvertes > Plus

Actualités

Le Dr Guy Sauvageau et son équipe sont nommés « Personnalité de la semaine» par La Presse  > Plus

Calendrier

  • 23 octobre 2014 11:00L'IRIC sur la route: University of Western Ontario - 2014 Grad Fair
  • 27 octobre 2014 11:30Endosomal generation of cAMP in GPCR signaling
  • 3 novembre 2014 11:30Controlling Phosphatases Through Unfair Competition
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Publications Récentes

Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases' occurrence.Medimegh I et al.Med. Oncol. 2014. > Plus

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.Bordeleau ME et al.Blood 2014. > Plus

Structural Maintenance of Chromosome (SMC) Proteins Link Microtubule Stability to Genome Integrity.Laflamme G et al.J. Biol. Chem. 2014. > Plus

Dimerization-induced allostery in protein kinase regulation.Lavoie H et al.Trends Biochem. Sci. 2014. > Plus

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin.Armando S et al.FASEB J. 2014. > Plus

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.Fares I et al.Science 2014. > Plus

Expression and functions of galectin-7 in ovarian cancer.Labrie M et al.Oncotarget 2014. > Plus

The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4+ CD8+ Thymocyte Survival.Marquis M et al.Mol. Cell. Biol. 2014. > Plus

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.Bouchekioua-Bouzaghou K et al.Int. J. Cancer 2014. > Plus

Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.Blanchet MF et al.Nucleic Acids Res. 2014. > Plus

Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS.Beautrait A et al.J. Biol. Chem. 2014. > Plus