35 résultats
SUN2 Modulates the Propagation of HSV-1.
Cruz-Palomar K, Hawkins J, Vandal C, Quenneville J, Gagnon E, Lippé R
J Virol
2022-05-11
;96(
9
):e0045322.
MHC class I antigen cross-presentation mediated by PapMV nanoparticles in human antigen-presenting cells is dependent on autophagy.
Possamaï D, Hanafi LA, Bellemare-Pelletier A, Hamelin K, Thébault P, Hébert MJ, Gagnon E, Leclerc D, Lapointe R
PLoS One
2021-12-31
;16(
12
):e0261987.
CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.
Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon E, Lemieux S, Perreault C
PLoS Comput Biol
2021-10-22
;17(
10
):e1009482.
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Igelmann S, Lessard F, Uchenunu O, Bouchard J, Fernandez-Ruiz A, Rowell MC, Lopes-Paciencia S, Papadopoli D, Fouillen A, Ponce KJ, Huot G, Mignacca L, Benfdil M, Kalegari P, Wahba HM, Pencik J, Vuong N, Quenneville J, Guillon J, Bourdeau V, Hulea L, Gagnon E, Kenner L, Moriggl R, Nanci A, Pollak MN, Omichinski JG, Topisirovic I, Ferbeyre G
Mol Cell
2021-09-16
;81(
18
):3848-3865.e19.
CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21.
Possamaï D, Pagé G, Panès R, Gagnon E, Lapointe R
J Immunol
2021-07-01
;207(
1
):77-89.
TMEM16F mediates bystander TCR-CD3 membrane dissociation at the immunological synapse and potentiates T cell activation.
Connolly A, Panes R, Tual M, Lafortune R, Bellemare-Pelletier A, Gagnon E
Sci Signal
2021-03-23
;14(
675
):.
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S
Proc. Natl. Acad. Sci. U.S.A.
2019-12-24
;116(
51
):25839-25849.
Electrostatic interactions: From immune receptor assembly to signaling.
Connolly A, Gagnon E
Immunol. Rev.
2019-09-01
;291(
1
):26-43.
The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole.
Arango Duque G, Jardim A, Gagnon E, Fukuda M, Descoteaux A
PLoS Pathog.
2019-07-29
;15(
7
):e1007982.
The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides.
Yan Y, Acevedo M, Mignacca L, Desjardins P, Scott N, Imane R, Quenneville J, Robitaille J, Feghaly A, Gagnon E, Ferbeyre G, Major F
Nucleic Acids Res.
2018-09-19
;46(
16
):8181-8196.
Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect.
Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader S
Proc. Natl. Acad. Sci. U.S.A.
2018-03-13
;115(
11
):E2653-E2662.
Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus.
Dumont-Lagacé M, Gerbe H, Daouda T, Laverdure JP, Brochu S, Lemieux S, Gagnon E, Perreault C
Front Immunol
2017-12-05
;8:1717.
Modeling human MLL-AF9 translocated acute myeloid leukemia from single donors reveals RET as a potential therapeutic target.
Barabé F, Gil L, Celton M, Bergeron A, Lamontagne V, Roques É, Lagacé K, Forest A, Johnson R, Pécheux L, Simard J, Pelloux J, Bellemare-Pelletier A, Gagnon E, Hébert J, Cellot S, Wilhelm B
Leukemia
2017-05-01
;31(
5
):1166-1176.
Studying Dynamic Plasma Membrane Binding of TCR-CD3 Chains During Immunological Synapse Formation Using Donor-Quenching FRET and FLIM-FRET.
Gagnon E, Connolly A, Dobbins J, Wucherpfennig KW
Methods Mol. Biol.
2017-03-03
;1584:259-289.
Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling.
Dobbins J, Gagnon E, Godec J, Pyrdol J, Vignali DA, Sharpe AH, Wucherpfennig KW
Sci Signal
2016-07-26
;9(
438
):ra75.
Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.
Matheoud D, Sugiura A, Bellemare-Pelletier A, Laplante A, Rondeau C, Chemali M, Fazel A, Bergeron JJ, Trudeau LE, Burelle Y, Gagnon E, McBride HM, Desjardins M
Cell
2016-07-14
;166(
2
):314-27.
Membrane Association of the CD3ε Signaling Domain Is Required for Optimal T Cell Development and Function.
Bettini ML, Guy C, Dash P, Vignali KM, Hamm DE, Dobbins J, Gagnon E, Thomas PG, Wucherpfennig KW, Vignali DA
J. Immunol.
2014-07-01
;193(
1
):258-67.
Leishmania Evades Host Immunity by Inhibiting Antigen Cross-Presentation through Direct Cleavage of the SNARE VAMP8.
Matheoud D, Moradin N, Bellemare-Pelletier A, Shio MT, Hong WJ, Olivier M, Gagnon E, Desjardins M, Descoteaux A
Cell Host Microbe
2013-07-17
;14(
1
):15-25.
Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3{varepsilon} cytoplasmic domain.
Gagnon E, Schubert DA, Gordo S, Chu HH, Wucherpfennig KW
J. Exp. Med.
2012-12-17
;209(
13
):2423-39.
β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation.
Kreslavsky T, Gleimer M, Miyazaki M, Choi Y, Gagnon E, Murre C, Sicinski P, von Boehmer H
Immunity
2012-11-16
;37(
5
):840-53.
Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.
Janas MM, Wang B, Harris AS, Aguiar M, Shaffer JM, Subrahmanyam YV, Behlke MA, Wucherpfennig KW, Gygi SP, Gagnon E, Novina CD
RNA
2012-11-01
;18(
11
):2041-55.
Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome.
Campbell-Valois FX, Trost M, Chemali M, Dill BD, Laplante A, Duclos S, Sadeghi S, Rondeau C, Morrow IC, Bell C, Gagnon E, Hatsuzawa K, Thibault P, Desjardins M
Mol. Cell Proteomics
2012-07-01
;11(
7
):M111.016378.
The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity.
Meissner TB, Li A, Liu YJ, Gagnon E, Kobayashi KS
Biochem. Biophys. Res. Commun.
2012-02-24
;418(
4
):786-91.
Self-reactive human CD4 T cell clones form unusual immunological synapses.
Schubert DA, Gordo S, Sabatino JJ, Vardhana S, Gagnon E, Sethi DK, Seth NP, Choudhuri K, Reijonen H, Nepom GT, Evavold BD, Dustin ML, Wucherpfennig KW
J. Exp. Med.
2012-02-13
;209(
2
):335-52.
Response multilayered control of T cell receptor phosphorylation.
Gagnon E, Xu C, Yang W, Chu HH, Call ME, Chou JJ, Wucherpfennig KW
Cell
2010-09-03
;142(
5
):669-71.
Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling.
Wucherpfennig KW, Gagnon E, Call MJ, Huseby ES, Call ME
Cold Spring Harb Perspect Biol
2010-04-01
;2(
4
):a005140.
Positively selecting peptides: their job does not end in the thymus.
Wucherpfennig KW, Gagnon E
Nat. Immunol.
2009-11-01
;10(
11
):1143-4.
Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif.
Xu C, Gagnon E, Call ME, Schnell JR, Schwieters CD, Carman CV, Chou JJ, Wucherpfennig KW
Cell
2008-11-14
;135(
4
):702-13.
Phagocytosis: the convoluted way from nutrition to adaptive immunity.
Desjardins M, Houde M, Gagnon E
Immunol. Rev.
2005-10-01
;207:158-65.
ER-mediated phagocytosis: myth or reality?
Gagnon E, Bergeron JJ, Desjardins M
J. Leukoc. Biol.
2005-06-01
;77(
6
):843-5.
Organelle proteomics: looking at less to see more.
Brunet S, Thibault P, Gagnon E, Kearney P, Bergeron JJ, Desjardins M
Drug Discov. Today
2004-01-15
;9(
2 Suppl
):S8-18.
Organelle proteomics: looking at less to see more.
Brunet S, Thibault P, Gagnon E, Kearney P, Bergeron JJ, Desjardins M
Trends Cell Biol.
2003-12-01
;13(
12
):629-38.
Phagosomes are competent organelles for antigen cross-presentation.
Houde M, Bertholet S, Gagnon E, Brunet S, Goyette G, Laplante A, Princiotta MF, Thibault P, Sacks D, Desjardins M
Nature
2003-09-25
;425(
6956
):402-6.
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages.
Gagnon E, Duclos S, Rondeau C, Chevet E, Cameron PH, Steele-Mortimer O, Paiement J, Bergeron JJ, Desjardins M
Cell
2002-07-12
;110(
1
):119-31.
The phagosome proteome: insight into phagosome functions.
Garin J, Diez R, Kieffer S, Dermine JF, Duclos S, Gagnon E, Sadoul R, Rondeau C, Desjardins M
J. Cell Biol.
2001-01-08
;152(
1
):165-80.