184 résultats
CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.
Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon E, Lemieux S, Perreault C
PLoS Comput Biol
2021-10-22
;17(
10
):e1009482.
PSMB11 regulates gene expression in cortical thymic epithelial cells.
Apavaloaei A, Laverdure JP, Perreault C
Cell Rep
2021-09-07
;36(
10
):109546.
Beneficial autoimmunity improves cancer prognosis.
Zitvogel L, Perreault C, Finn OJ, Kroemer G
Nat Rev Clin Oncol
2021-09-01
;18(
9
):591-602.
A bacterium-derived, cancer-associated immunopeptidome.
Perreault C, Thibault P, Kroemer G
Oncoimmunology
2021-05-03
;10(
1
):1918373.
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C
Immunity
2021-04-13
;54(
4
):737-752.e10.
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.
Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil E, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW
Cell Rep
2021-03-09
;34(
10
):108815.
UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.
Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, Lemieux S, Perreault C, Rodier F, Dufresne SF, Busque L, Lachance S, Sauvageau G, Cohen S, Delisle JS
Transplant Cell Ther
2021-01-01
;27(
1
):76.e1-76.e9.
A Roadmap Toward the Definition of Actionable Tumor-Specific Antigens.
Minati R, Perreault C, Thibault P
Front Immunol
2020-12-03
;11:583287.
Major multilevel molecular divergence between THP-1 cells from different biorepositories.
Noronha N, Ehx G, Meunier MC, Laverdure JP, Thériault C, Perreault C
Int. J. Cancer
2020-10-01
;147(
7
):2000-2006.
The Origin and Immune Recognition of Tumor-Specific Antigens.
Apavaloaei A, Hardy MP, Thibault P, Perreault C
Cancers (Basel)
2020-09-12
;12(
9
):.
IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.
Benhammadi M, Mathé J, Dumont-Lagacé M, Kobayashi KS, Gaboury L, Brochu S, Perreault C
J. Immunol.
2020-09-01
;205(
5
):1268-1280.
Apoptotic exosome-like vesicles regulate endothelial gene expression, inflammatory signaling, and function through the NF-κB signaling pathway.
Migneault F, Dieudé M, Turgeon J, Beillevaire D, Hardy MP, Brodeur A, Thibodeau N, Perreault C, Hébert MJ
Sci Rep
2020-07-28
;10(
1
):12562.
Extending the Comprehensiveness of Immunopeptidome Analyses Using Isobaric Peptide Labeling.
Pfammatter S, Bonneil E, Lanoix J, Vincent K, Hardy MP, Courcelles M, Perreault C, Thibault P
Anal. Chem.
2020-07-07
;92(
13
):9194-9204.
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition.
Trofimov A, Cohen JP, Bengio Y, Perreault C, Lemieux S
Bioinformatics
2020-07-01
;36(
Supplement_1
):i417-i426.
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues.
Larouche JD, Trofimov A, Hesnard L, Ehx G, Zhao Q, Vincent K, Durette C, Gendron P, Laverdure JP, Bonneil E, Côté C, Lemieux S, Thibault P, Perreault C
Genome Med
2020-04-28
;12(
1
):40.
MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses.
Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P
J. Proteome Res.
2020-04-03
;19(
4
):1873-1881.
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil E, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C
Cancer Immunol Res
2020-04-03
;8(
4
):544-555.
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration.
Dumont-Lagacé M, Daouda T, Depoërs L, Zumer J, Benslimane Y, Brochu S, Harrington L, Lemieux S, Perreault C
Front Immunol
2020-02-11
;10:3118.
The Genomic Landscape of Antigenic Targets for T Cell-Based Leukemia Immunotherapy.
Hardy MP, Vincent K, Perreault C
Front Immunol
2020-01-13
;10:2934.
Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis.
Roy DC, Lachance S, Cohen S, Delisle JS, Kiss T, Sauvageau G, Busque L, Ahmad I, Bernard L, Bambace N, Boumédine RS, Guertin MC, Rezvani K, Mielke S, Perreault C, Roy J
Br. J. Haematol.
2019-09-01
;186(
5
):754-766.
Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs.
Hardy MP, Audemard É, Migneault F, Feghaly A, Brochu S, Gendron P, Boilard É, Major F, Dieudé M, Hébert MJ, Perreault C
Sci Rep
2019-05-10
;9(
1
):7203.
Discovery and characterization of actionable tumor antigens.
Ehx G, Perreault C
Genome Med
2019-04-30
;11(
1
):29.
PSMB11 Orchestrates the Development of CD4 and CD8 Thymocytes via Regulation of Gene Expression in Cortical Thymic Epithelial Cells.
Apavaloaei A, Brochu S, Dong M, Rouette A, Hardy MP, Villafano G, Murata S, Melichar HJ, Perreault C
J. Immunol.
2018-12-19
;.
Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C
Sci Transl Med
2018-12-05
;10(
470
):.
Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.
Lanoix J, Durette C, Courcelles M, Cossette É, Comtois-Marotte S, Hardy MP, Côté C, Perreault C, Thibault P
Proteomics
2018-06-01
;18(
12
):e1700251.
Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.
Laumont CM, Perreault C
Cell. Mol. Life Sci.
2018-02-01
;75(
4
):607-621.
The SysteMHC Atlas project.
Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R, Caron E
Nucleic Acids Res.
2018-01-04
;46(
D1
):D1237-D1247.
Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus.
Dumont-Lagacé M, Gerbe H, Daouda T, Laverdure JP, Brochu S, Lemieux S, Gagnon E, Perreault C
Front Immunol
2017-12-05
;8:1717.
Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.
St-Pierre C, Morgand E, Benhammadi M, Rouette A, Hardy MP, Gaboury L, Perreault C
Cell Rep
2017-11-28
;21(
9
):2558-2570.
Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance.
Bloy N, Garcia P, Laumont CM, Pitt JM, Sistigu A, Stoll G, Yamazaki T, Bonneil E, Buqué A, Humeau J, Drijfhout JW, Meurice G, Walter S, Fritsche J, Weinschenk T, Rammensee HG, Melief C, Thibault P, Perreault C, Pol J, Zitvogel L, Senovilla L, Kroemer G
Immunol. Rev.
2017-11-01
;280(
1
):165-174.
An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation.
Collin R, St-Pierre C, Guilbault L, Mullins-Dansereau V, Policheni A, Guimont-Desrochers F, Pelletier AN, Gray DH, Drobetsky E, Perreault C, Hillhouse EE, Lesage S
J. Immunol.
2017-08-15
;199(
4
):1490-1504.
Major vs minor histocompatibility antigens.
Roy DC, Perreault C
Blood
2017-02-09
;129(
6
):664-666.
MHC class I-associated peptides derive from selective regions of the human genome.
Pearson H, Daouda T, Granados DP, Durette C, Bonneil E, Courcelles M, Rodenbrock A, Laverdure JP, Côté C, Mader S, Lemieux S, Thibault P, Perreault C
J. Clin. Invest.
2016-12-01
;126(
12
):4690-4701.
Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers.
Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault C
Sci Rep
2016-09-23
;6:34019.
ERAAP Shapes the Peptidome Associated with Classical and Nonclassical MHC Class I Molecules.
Nagarajan NA, de Verteuil DA, Sriranganadane D, Yahyaoui W, Thibault P, Perreault C, Shastri N
J. Immunol.
2016-08-15
;197(
4
):1035-43.
Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers.
Granados DP, Rodenbrock A, Laverdure JP, Côté C, Caron-Lizotte O, Carli C, Pearson H, Janelle V, Durette C, Bonneil E, Roy DC, Delisle JS, Lemieux S, Thibault P, Perreault C
Leukemia
2016-06-01
;30(
6
):1344-54.
Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile.
Patenaude J, Perreault C
J. Immunol.
2016-06-01
;196(
11
):4760-70.
Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames.
Laumont CM, Daouda T, Laverdure JP, Bonneil É, Caron-Lizotte O, Hardy MP, Granados DP, Durette C, Lemieux S, Thibault P, Perreault C
Nat Commun
2016-01-01
;7:10238.
pyGeno: A Python package for precision medicine and proteogenomics.
Daouda T, Perreault C, Lemieux S
F1000Res
2016-01-01
;5:381.
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection.
Dieudé M, Bell C, Turgeon J, Beillevaire D, Pomerleau L, Yang B, Hamelin K, Qi S, Pallet N, Béland C, Dhahri W, Cailhier JF, Rousseau M, Duchez AC, Lévesque T, Lau A, Rondeau C, Gingras D, Muruve D, Rivard A, Cardinal H, Perreault C, Desjardins M, Boilard É, Thibault P, Hébert MJ
Sci Transl Med
2015-12-16
;7(
318
):318ra200.
Sex hormones have pervasive effects on thymic epithelial cells.
Dumont-Lagacé M, St-Pierre C, Perreault C
Sci Rep
2015-08-07
;5:12895.
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells.
St-Pierre C, Trofimov A, Brochu S, Lemieux S, Perreault C
J. Immunol.
2015-07-15
;195(
2
):498-506.
The Perlecan Fragment LG3 Regulates Homing of Mesenchymal Stem Cells and Neointima Formation During Vascular Rejection.
Pilon EA, Dieudé M, Qi S, Hamelin K, Pomerleau L, Beillevaire D, Durocher Y, Zutter M, Coutu D, Perreault C, Hébert MJ
Am. J. Transplant.
2015-05-01
;15(
5
):1205-18.
The nature of self for T cells-a systems-level perspective.
Granados DP, Laumont CM, Thibault P, Perreault C
Curr. Opin. Immunol.
2014-11-15
;34C:1-8.
Immunoproteasomes shape the transcriptome and regulate the function of dendritic cells.
de Verteuil DA, Rouette A, Hardy MP, Lavallée S, Trofimov A, Gaucher E, Perreault C
J. Immunol.
2014-08-01
;193(
3
):1121-32.
The immunopeptidome of normal and neoplastic cells.
Perreault C, Granados D, Laumont C, Thibault P
Exp. Hematol.
2014-08-01
;42(
8 Suppl
):S5.
Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides.
Granados DP, Sriranganadane D, Daouda T, Zieger A, Laumont CM, Caron-Lizotte O, Boucher G, Hardy MP, Gendron P, Côté C, Lemieux S, Thibault P, Perreault C
Nat Commun
2014-04-09
;5:3600.
Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimullerian hormone expression during oocyte maturation in the female follicle.
Prunskaite-Hyyryläinen R, Shan J, Railo A, Heinonen KM, Miinalainen I, Yan W, Shen B, Perreault C, Vainio SJ
FASEB J.
2014-04-01
;28(
4
):1568-81.
Adult thymic epithelium contains nonsenescent label-retaining cells.
Dumont-Lagacé M, Brochu S, St-Pierre C, Perreault C
J. Immunol.
2014-03-01
;192(
5
):2219-26.
Rejection of leukemic cells requires antigen-specific t cells with high functional avidity.
Vincent K, Hardy MP, Trofimov A, Laumont CM, Sriranganadane D, Hadj-Mimoune S, Salem Fourati I, Soudeyns H, Thibault P, Perreault C
Biol. Blood Marrow Transplant.
2014-01-01
;20(
1
):37-45.