260 résultats
SUMO Proteomics Analyses Identify Protein Inhibitor of Activated STAT-Mediated Regulatory Networks Involved in Cell Cycle and Cell Proliferation.
Li C, Boutet A, Pascariu CM, Nelson T, Courcelles M, Wu Z, Comtois-Marotte S, Emery G, Thibault P
J Proteome Res
2023-03-03
;22(
3
):812-825.
Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro.
Li ASM, Homsi C, Bonneil E, Thibault P, Verreault A, Vedadi M
Biochim Biophys Acta Gene Regul Mech
2023-02-21
;1866(
2
):194922.
RNA helicase DDX3X modulates herpes simplex virus 1 nuclear egress.
Khadivjam B, Bonneil E, Thibault P, Lippé R
Commun Biol
2023-02-01
;6(
1
):134.
Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy.
Javary J, Goupil E, Soulez M, Kanshin E, Bouchard A, Seternes OM, Thibault P, Labbé J, Meloche S
J Cell Physiol
2022-12-28
;.
Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells.
Wu Z, Bonneil E, Belford M, Boeser C, Ruiz Cuevas MV, Lemieux S, Dunyach JJ, Thibault P
Anal Chem
2022-09-06
;94(
35
):12086-12094.
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers.
Apavaloaei A, Hesnard L, Hardy MP, Benabdallah B, Ehx G, Thériault C, Laverdure JP, Durette C, Lanoix J, Courcelles M, Noronha N, Chauhan KD, Lemieux S, Beauséjour C, Bhatia M, Thibault P, Perreault C
Cell Rep
2022-08-16
;40(
7
):111241.
Immunopeptidomics: Reading the Immune Signal That Defines Self From Nonself.
Thibault P, Perreault C
Mol Cell Proteomics
2022-05-11
;21(
6
):100234.
Head-to-tail cyclization of side chain-protected linear peptides to recapitulate genetically-encoded cyclized peptides.
Bouayad-Gervais S, St-Cyr DJ, Courcelles M, Bonneil E, Gohard FH, Thibault P, Earnshaw WC, Tyers M
Pept Sci (Hoboken)
2022-05-01
;114(
3
):e24254.
Immunopeptidomic analyses of colorectal cancers with and without microsatellite instability.
Cleyle J, Hardy MP, Minati R, Courcelles M, Durette C, Lanoix J, Laverdure JP, Vincent K, Perreault C, Thibault P
Mol Cell Proteomics
2022-05-01
;21(
5
):100228.
The microprotein Nrs1 rewires the G1/S transcriptional machinery during nitrogen limitation in budding yeast.
Tollis S, Singh J, Palou R, Thattikota Y, Ghazal G, Coulombe-Huntington J, Tang X, Moore S, Blake D, Bonneil E, Royer CA, Thibault P, Tyers M
PLoS Biol
2022-03-01
;20(
3
):e3001548.
Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes.
Beillevaire D, Migneault F, Turgeon J, Gingras D, Rimbaud AK, Marcoux G, Spino C, Thibodeau N, Bonneil E, Thibault P, Boilard E, Dieudé M, Hébert MJ
Cell Death Dis
2022-02-11
;13(
2
):145.
MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets.
Kovalchik KA, Ma Q, Wessling L, Saab F, D Duquette J, Kubiniok P, Hamelin DJ, Faridi P, Li C, Purcell AW, Jang A, Paramithiotis E, Tognetti M, Reiter L, Bruderer R, Lanoix J, Bonneil E, Courcelles M, Thibault P, Caron E, Sirois I
Mol Cell Proteomics
2021-11-17
;21(
1
):100178.
CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.
Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon E, Lemieux S, Perreault C
PLoS Comput Biol
2021-10-22
;17(
10
):e1009482.
Early defects in mucopolysaccharidosis type IIIC disrupt excitatory synaptic transmission.
Pará C, Bose P, Bruno L, Freemantle E, Taherzadeh M, Pan X, Han C, McPherson PS, Lacaille JC, Bonneil E, Thibault P, O'Leary C, Bigger B, Morales CR, Di Cristo G, Pshezhetsky AV
JCI Insight
2021-08-09
;6(
15
):.
Proteomic strategies for characterizing ubiquitin-like modifications
Chongyang Li, Trent G. Nelson, Thibault P
2021-07-29
;1(
53
):.
Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q-Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer.
Pfammatter S, Wu Z, Bonneil E, Bailey DJ, Prasad S, Belford M, Rochon J, Picard P, Lacoursière J, Dunyach JJ, Thibault P
Anal Chem
2021-07-20
;93(
28
):9817-9825.
A bacterium-derived, cancer-associated immunopeptidome.
Perreault C, Thibault P, Kroemer G
Oncoimmunology
2021-05-03
;10(
1
):1918373.
Crosstalk Between SUMO and Ubiquitin-Like Proteins: Implication for Antiviral Defense.
Chelbi-Alix MK, Thibault P
Front Cell Dev Biol
2021-04-21
;9:671067.
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C
Immunity
2021-04-13
;54(
4
):737-752.e10.
SUMOylation- and GAR1-Dependent Regulation of Dyskerin Nuclear and Subnuclear Localization.
MacNeil DE, Lambert-Lanteigne P, Qin J, McManus FP, Bonneil E, Thibault P, Autexier C
Mol Cell Biol
2021-03-24
;41(
4
):.
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.
Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil E, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW
Cell Rep
2021-03-09
;34(
10
):108815.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.
Benslimane Y, Sánchez-Osuna M, Coulombe-Huntington J, Bertomeu T, Henry D, Huard C, Bonneil E, Thibault P, Tyers M, Harrington L
Aging Cell
2021-03-04
;e13331.
UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.
Chagraoui J, Girard S, Spinella JF, Simon L, Bonneil E, Mayotte N, MacRae T, Coulombe-Huntington J, Bertomeu T, Moison C, Tomellini E, Thibault P, Tyers M, Marinier A, Sauvageau G
Cell Stem Cell
2021-01-07
;28(
1
):48-62.e6.
A Roadmap Toward the Definition of Actionable Tumor-Specific Antigens.
Minati R, Perreault C, Thibault P
Front Immunol
2020-12-03
;11:583287.
H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.
Khazaei S, De Jay N, Deshmukh S, Hendrikse LD, Jawhar W, Chen CCL, Mikael LG, Faury D, Marchione DM, Lanoix J, Bonneil E, Ishii T, Jain SU, Rossokhata K, Sihota TS, Eveleigh R, Lisi V, Harutyunyan AS, Jung S, Karamchandani J, Dickson BC, Turcotte R, Wunder JS, Thibault P, Lewis PW, Garcia BA, Mack SC, Taylor MD, Garzia L, Kleinman CL, Jabado N
Cancer Discov
2020-12-01
;10(
12
):1968-1987.
Proteomics of Herpes Simplex Virus Type 1 Nuclear Capsids.
El Bilali N, Khadivjam B, Bonneil E, Thibault P, Lippé R
J Virol
2020-11-25
;95(
4
):e01842-19.
Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis.
Garrido D, Bourouh M, Bonneil E, Thibault P, Swan A, Archambault V
PLoS Genet
2020-11-02
;16(
11
):e1009184.
Blood extracellular vesicles from healthy individuals regulate hematopoietic stem cells as humans age.
Grenier-Pleau I, Tyryshkin K, Le TD, Rudan J, Bonneil E, Thibault P, Zeng K, Lässer C, Mallinson D, Lamprou D, Hui J, Postovit LM, Chan EYW, Abraham SA
Aging Cell
2020-10-07
;e13245.
The Origin and Immune Recognition of Tumor-Specific Antigens.
Apavaloaei A, Hardy MP, Thibault P, Perreault C
Cancers (Basel)
2020-09-12
;12(
9
):.
Extending the Comprehensiveness of Immunopeptidome Analyses Using Isobaric Peptide Labeling.
Pfammatter S, Bonneil E, Lanoix J, Vincent K, Hardy MP, Courcelles M, Perreault C, Thibault P
Anal. Chem.
2020-07-07
;92(
13
):9194-9204.
Interferon, restriction factors and SUMO pathways.
El-Asmi F, McManus FP, Thibault P, Chelbi-Alix MK
Cytokine Growth Factor Rev.
2020-05-08
;.
Interplay of Ubiquitin-Like Modifiers Following Arsenic Trioxide Treatment.
Rinfret Robert C, McManus FP, Lamoliatte F, Thibault P
J. Proteome Res.
2020-05-01
;19(
5
):1999-2010.
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues.
Larouche JD, Trofimov A, Hesnard L, Ehx G, Zhao Q, Vincent K, Durette C, Gendron P, Laverdure JP, Bonneil E, Côté C, Lemieux S, Thibault P, Perreault C
Genome Med
2020-04-28
;12(
1
):40.
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development.
Jacques S, van der Sloot AM, C Huard C, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD, Tyers M
Genetics
2020-04-15
;214(
4
):1103-1120.
MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses.
Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P
J. Proteome Res.
2020-04-03
;19(
4
):1873-1881.
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil E, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C
Cancer Immunol Res
2020-04-03
;8(
4
):544-555.
Cross-talk between SUMOylation and ISGylation in response to interferon.
El-Asmi F, McManus FP, Brantis-de-Carvalho CE, Valle-Casuso JC, Thibault P, Chelbi-Alix MK
Cytokine
2020-02-17
;129:155025.
Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility.
Li C, McManus FP, Plutoni C, Pascariu CM, Nelson T, Alberici Delsin LE, Emery G, Thibault P
Nat Commun
2020-02-14
;11(
1
):834.
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, Lavallée VP, Kanshin E, Bertomeu T, Coulombe-Huntington J, St-Denis C, Bordeleau ME, Boucher G, Roux PP, Lemieux S, Tyers M, Thibault P, Hébert J, Marinier A, Sauvageau G
Cancer Cell
2019-07-08
;36(
1
):84-99.e8.
Accurate Quantitative Proteomic Analyses Using Metabolic Labeling and High Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS).
Pfammatter S, Bonneil E, McManus FP, Thibault P
J. Proteome Res.
2019-05-03
;18(
5
):2129-2138.
Rapid detection of Bacillus ionophore cereulide in food products.
Ducrest PJ, Pfammatter S, Stephan D, Vogel G, Thibault P, Schnyder B
Sci Rep
2019-04-09
;9(
1
):5814.
Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs.
Kubiniok P, Finicle BT, Piffaretti F, McCracken AN, Perryman M, Hanessian S, Edinger AL, Thibault P
Mol. Cell Proteomics
2019-03-01
;18(
3
):408-422.
Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C
Sci Transl Med
2018-12-05
;10(
470
):.
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.
Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB
Nat Commun
2018-10-22
;9(
1
):4385.
Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection.
Cheng X, Jobin-Robitaille O, Billon P, Buisson R, Niu H, Lacoste N, Abshiru N, Côté V, Thibault P, Kron SJ, Sung P, Brandl CJ, Masson JY, Côté J
Proc. Natl. Acad. Sci. U.S.A.
2018-10-02
;115(
40
):10028-10033.
A Novel Differential Ion Mobility Device Expands the Depth of Proteome Coverage and the Sensitivity of Multiplex Proteomic Measurements.
Pfammatter S, Bonneil E, McManus FP, Prasad S, Bailey DJ, Belford M, Dunyach JJ, Thibault P
Mol. Cell Proteomics
2018-10-01
;17(
10
):2051-2067.
Combined Enrichment/Enzymatic Approach To Study Tightly Clustered Multisite Phosphorylation on Ser-Rich Domains.
Kanshin E, Pascariu M, Tyers M, D'Amours D, Thibault P
J. Proteome Res.
2018-09-07
;17(
9
):3050-3060.
Meet the Editors: Pierre Thibault.
Thibault P
Rapid Commun. Mass Spectrom.
2018-08-30
;32(
16
):1320-1321.
PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells.
Kim SM, Nguyen TT, Ravi A, Kubiniok P, Finicle BT, Jayashankar V, Malacrida L, Hou J, Robertson J, Gao D, Chernoff J, Digman MA, Potma EO, Tromberg BJ, Thibault P, Edinger AL
Cancer Discov
2018-07-01
;8(
7
):866-883.
Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.
Lanoix J, Durette C, Courcelles M, Cossette É, Comtois-Marotte S, Hardy MP, Côté C, Perreault C, Thibault P
Proteomics
2018-06-01
;18(
12
):e1700251.