Publication — IRIC

Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.

Celastrol, a triterpene from plants, has been used in traditional oriental medicine to treat various diseases. Here, we investigated the cardioprotective effects of celastrol against ischaemia.

Date de publication
1er décembre 2014
Chercheurs
Der Sarkissian S, Cailhier JF, Borie M, Stevens LM, Gaboury L, Mansour S, Hamet P, Noiseux N
Référence PubMed
Br. J. Pharmacol. 2014;171(23):5265-79
ID PubMed
25041185
Affiliation
Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada; Department of Surgery, Université de Montréal, Montreal, Quebec, Canada.