Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.

Publication — IRIC

Celastrol, a triterpene from plants, has been used in traditional oriental medicine to treat various diseases. Here, we investigated the cardioprotective effects of celastrol against ischaemia.

Date de publication: 1^er décembre 2014
Chercheur(euse)s: Der Sarkissian S, Cailhier JF, Borie M, Stevens LM, Gaboury L, Mansour S, Hamet P, Noiseux N
Référence PubMed: Br. J. Pharmacol. 2014;171(23):5265-79
ID PubMed: 25041185
Affiliation: Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada; Department of Surgery, Université de Montréal, Montreal, Quebec, Canada.