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  • 31 October 2022

    Cancer cells hijack RNA processing to rewrite the message.

    Borden K
    Biochem Soc Trans 2022-10-31 ;50( 5 ):1447-1456.

  • 29 October 2022

    CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma.

    Houles T, Lavoie G, Nourreddine S, Cheung W, Vaillancourt-Jean E, Guérin CM, Bouttier M, Grondin B, Lin S, Saba-El-Leil MK, Angers S, Meloche S, Roux PP
    Nat Commun 2022-10-29 ;13( 1 ):6457.

  • 14 October 2022

    Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure-Function Post Myocardial Infarction.

    Lupisella J, St-Onge S, Carrier M, Cook EM, Wang T, Sum C, Fernando G, Apgar K, Zhang R, Carson N, Snyder BJ, Ryan CS, Ma X, Dierks EA, Little S, Kick EK, Wurtz NR, Bouvier M, Héroux M, Garcia RA
    ACS Pharmacol Transl Sci 2022-10-14 ;5( 10 ):892-906.

  • 13 October 2022

    Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.

    Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F
    J Med Chem 2022-10-13 ;65( 19 ):12725-12746.

  • 12 October 2022

    Impact of Implementing a Bendamustine-based Conditioning Regimen on outcomes of Autologous Stem Cell Transplant in Lymphoma while Novel Cellular Therapies Emerge.

    Lachance S, Bourguignon A, Boisjoly JA, Bouchard P, Ahmad I, Bambace N, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Veilleux O, Zehr J, Chagnon M, Roy J
    Transplant Cell Ther 2022-10-12 ;.

  • 5 October 2022

    Overview of the COVID-19 text mining tool interactive demonstration track in BioCreative VII.

    Chatr-Aryamontri A, Hirschman L, Ross KE, Oughtred R, Krallinger M, Dolinski K, Tyers M, Korves T, Arighi CN
    Database (Oxford) 2022-10-05 ;2022:.

  • 3 October 2022

    New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.

    Merali S, Wang Z, Frost C, Callejo M, Hedrick M, Hui L, Meadows Shropshire S, Xu K, Bouvier M, DeSouza MM, Yang J
    Platelets 2022-10-03 ;33( 7 ):969-978.

  • 30 September 2022

    Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.

    Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P
    Science 2022-09-30 ;377( 6614 ):eabn7065.

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