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  • 30 juin 2025

    Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis.

    Zhou F, Culjkovic-Kraljacic B, Bach C, Feng L, Mishima Y, Borden K, Tenen DG
    Blood Neoplasia 2025-06-30 ;2( 4 ):100132

  • 30 juin 2025

    Sphingosine simultaneously inhibits nuclear import and activates PP2A by binding importins and PPP2R1A.

    Jayashankar V, Kubiniok P, McCracken AN, Gentry RG, Eckenstein KH, Sernissi L, Vece V, Garsi JB, Valles SY, Jung S, Hoffman NC, Perrochon AS, Selwan EM, Finicle BT, Pitman M, Lin D, Bonneil E, Xu R, Mao C, Kaiser P, Fruman DA, Mobley D, Jang C, Hanessian S, Thibault P, Edinger AL
    EMBO J 2025-06-30 ;

  • 18 juin 2025

    Gender representation in professorship and research productivity across all surgical specialties in Canadian academic institutions.

    Tanya SM, Nguyen AX, Joly-Chevrier M, Pur DR, Sharma S, Costello F, Kherani F, Trinh VQ, Hardy I, Lando L
    Can J Surg 2025-06-18 ;68( 3 ):E253-E264

  • 12 juin 2025

    CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.

    Rodriguez MM, Chatterjee D, Guerry J, Patenaude AM, Cohen CCH, Bois T, Larouche A, Ferreira SR, Bertomeu T, Chatr-Aryamontri A, Zhang L, Mader S, Nislow C, St-Jean G, Guindon Y, Zahn A, Di Noia JM
    Proc Natl Acad Sci U S A 2025-06-12 ;122( 24 ):e2424409122

  • 11 juin 2025

    Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R.

    Morales-Pastor A, Miljuš T, Dieguez-Eceolaza M, Stępniewski TM, Ledesma-Martin V, Heydenreich FM, Flock T, Plouffe B, Le Gouill C, Duchaine J, Sykes DA, Nicholson C, Koers EJ, Guba W, Rufer AC, Grether U, Bouvier M, Veprintsev DB, Selent J
    Nat Commun 2025-06-11 ;16( 1 ):5265

  • 6 juin 2025

    CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond.

    Ismail H, Chagraoui J, Sauvageau G
    Sci Adv 2025-06-06 ;11( 23 ):eads6556

  • 29 mai 2025

    BRAF oncogenic mutants evade autoinhibition through a common mechanism.

    Lavoie H, Jin T, Lajoie D, Decossas M, Gendron P, Wang B, Filandr F, Sahmi M, Hwa Jo C, Weber S, Arseneault G, Tripathy S, Beaulieu P, Schuetz DA, Schriemer DC, Marinier A, Rice WJ, Maisonneuve P, Therrien M
    Science 2025-05-29 ;388( 6750 ):eadp2742

  • 28 mai 2025

    Gαs-specific structural elements attenuate interactions with regulator of G protein signaling (RGS) proteins.

    Higazy-Mreih S, Avital-Shacham M, LeGouill C, Bouvier M, Kosloff M
    FEBS J 2025-05-28 ;

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