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Publications

Publications récentes

  • 30 décembre 2025

    Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10.

    Corriveau J, Monot P, Delisle C, Goyette MA, Gasse C, El Bakkouri Y, Hoang T, Côté JF, Gratton JP
    Cell Rep 2025-12-30 ;45( 1 ):116840

  • 23 décembre 2025

    Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β-arrestin recruitment and the discovery of an allosteric agonist.

    Lind S, Wright SC, Gvozdenovic E, Nilsson K, Granberg KL, Bouvier M, Johansson LC
    Br J Pharmacol 2025-12-23 ;

  • 19 décembre 2025

    Screening apelin analogues and a small molecule agonist as effective cardiovascular therapeutics against reperfusion injury.

    Wijewardane A, Fernandez KX, Zhang A, Fischer C, Nagahawatta DP, Iturrioz X, Avet C, Heard BL, Llorens-Cortes C, Oudit GY, Bouvier M, Vederas JC
    RSC Med Chem 2025-12-19 ;

  • 12 décembre 2025

    CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

    Minati R, Cahuzac M, Perrault J, Lullier V, Apavaloaei A, Bonneil E, Courcelles M, Lanoix J, Kina E, Perreault C, Thibault P
    Cell Rep 2025-12-12 ;44( 12 ):116676

  • 1er décembre 2025

    Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.

    Grenier-Pleau IJ, Wells CJ, Holmes SM, Hall C, Vermeulen M, de Villiers CA, Penders J, Pedersen SV, Dick SA, Bonneil E, Slobodyanyuk M, Nagree MS, Kaur J, McNaughton AJM, Beaulieu J, Stevens MM, Xie SZ, Rauh MJ, Postovit LM, Knapp D, Reimand J, Tyryshkin K, Thibault P, Craig AW, Rudan JF, Mann S, Chan EYW, Abraham SA
    J Extracell Vesicles 2025-12-01 ;14( 12 ):e70181

  • 18 novembre 2025

    Development of a Genetically Encoded and Potent PDE6D Inhibitor.

    Gómez-Mulas A, Schaffner-Reckinger E, Peeters H, Chippalkatti R, Dautbasic A, Smith M, Ismail S, Abankwa DK
    Chembiochem 2025-11-18 ;e202500739

  • 11 novembre 2025

    Ubiquitination of MHC class II molecules regulates B-cell development and response to antigens in mice.

    Raymond M, Balthazard R, Zahn A, Silva-Barrios S, Hammami A, Majdoubi A, Lee JS, Connolly A, Sabourin A, Galbas T, Moulefera MA, Ogura H, Ishido S, Balood M, Talbot S, Gagnon E, Di Noia JM, Stäger S, Thibodeau J
    J Immunol 2025-11-11 ;

  • 10 novembre 2025

    CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy.

    Lehnertz B, Langouët M, Corneau S, MacRae T, Joe M, Schmidt EN, Spinella JF, Mayotte N, Moore S, Tellechea MF, Boivin I, Papineau L, Rojas-Sutterlin S, Tual M, Cortes CJ, Chagraoui J, Tomellini E, Desse V, Gagnon E, Macauley MS, Sauvageau G
    Mol Ther 2025-11-10 ;

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