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Publications

Publications récentes

  • 17 février 2026

    From Lead to Clinical Candidate: Discovery of BMS-986331 as a Potent and Selective N-Formyl Peptide Receptor 2 Agonist.

    Shirude PS, Cheney D, Chattopadhyay AK, Seshadri B, Baligar V, Rachamreddy C, Madduri S, Anjanappa P, Viet A, Valente MN, Rossi K, Abousleiman M, Hsu MY, Everlof G, Gali V, Sun Y, Allocco J, Zhang R, St-Onge S, Lupisella J, Chen XQ, Sarodaya S, Ravindran MS, Tagore DM, Nagar J, Dudhgaonkar S, Putlur S, Héroux M, Bouvier M, Wexler RR, Dierks E, Garcia RA, Kick EK, Wurtz NR
    J Med Chem 2026-02-17 ;

  • 30 janvier 2026

    A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

    Coulombe-Huntington J, Bertomeu T, Huard C, Chatr-Aryamontri A, St-Cyr DJ, Sánchez-Osuna M, Papadopoli D, Normandin K, Paydar M, McLaughlan S, St-Denis C, Zhang L, Say H, Palou R, Stark C, Breitkreutz BJ, van der Sloot AM, Manohar S, Lavoie H, Borden K, Raught B, D'Amours D, Sicheri F, Verreault A, Mader S, Meloche S, Therrien M, Thibault P, Wilhelm B, Dirks PB, Aitchison JD, Patton E, King RW, Roux PP, Sauvageau G, Hoang T, Marinier A, Harrington L, Kwok B, Archambault V, Topisirovic I, Tyers M
    bioRxiv 2026-01-30 ;

  • 24 janvier 2026

    Dual Targeting of IDH2 and the Ubiquitin-Proteasome System Reveals a Functional Vulnerability in Breast Cancer Models.

    Gharari N, Mereu E, Luciano B, Heidari B, Mader S, Piva R
    Cancers (Basel) 2026-01-24 ;18( 3 ):

  • 23 janvier 2026

    Early IKKβ-Dependent Anabolic Signature Governs Vascular Smooth Muscle Cells Fate and Abdominal Aortic Aneurysm Development.

    Doyon P, Kizilay Mancini O, Dô F, Huynh D, Mayer G, Lehoux S, Ong H, Batardière M, Trinh VQ, Wen Y, Tang W, Marleau S, Gravel SP, Servant MJ
    Cells 2026-01-23 ;15( 3 ):

  • 20 janvier 2026

    Rapidly Expanded EBV-Specific T Cells for the Treatment of Refractory EBV Reactivation and EBV-Related Lymphoproliferative Disorders.

    Schweitzer L, Thiant S, Thérien C, Giroux M, Lachance S, Fleury I, Orio J, Carli C, Boudreau G, Patenaude J, Tremblay-Laganière C, Senécal L, Dufresne SF, Mollica L, Collette S, Sauvageau G, Kiss T, Cohen S, Bernard L, Bambace N, Veilleux O, Ahmad I, Roy J, Busque L, Duval M, Bittencourt H, Teira P, Lamarche C, Roy DC, Delisle JS
    Open Forum Infect Dis 2026-01-20 ;13( 1 ):ofag006

  • 30 décembre 2025

    Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10.

    Corriveau J, Monot P, Delisle C, Goyette MA, Gasse C, El Bakkouri Y, Hoang T, Côté JF, Gratton JP
    Cell Rep 2025-12-30 ;45( 1 ):116840

  • 24 décembre 2025

    The GF-NEO discovery platform unveils a [KQE][DG] sequence motif within fusion neoantigens in pediatric cancer.

    Savoie C, Wu Z, Saab F, St-Laurent T, Thibault P, Beauparlant CB, Déry MA, El-Hachem N, Gharsallaoui B, Tremblay SJ, Sabouret A, Chauca Torres NE, Bilodeau M, Bonneil E, Sidney J, Sette A, Droit A, Thibault P, Cellot S, Caron E, Sirois I
    iScience 2025-12-24 ;29( 2 ):114512

  • 23 décembre 2025

    ADPv2: A hierarchical histological tissue type-annotated dataset for potential biomarker discovery of colorectal disease.

    Yang Z, Li K, Ramandi SG, Brassard P, Khellaf A, Trinh VQ, Zhang J, Chen L, Rowsell C, Varma S, Plataniotis K, Hosseini MS
    J Pathol Inform 2025-12-23 ;20:100537

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