IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc?Cell Stem Cell 2008-12-04;3(6):579-80.
Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.J. Cell. Physiol. 2008-12-01;217(3):778-88.
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation.Proc. Natl. Acad. Sci. U.S.A. 2008-11-11;105(45):17414-9.
Roux-en-Y diversion for intractable reflux after esophagectomy.Ann. Thorac. Surg. 2008-11-01;86(5):1646-52.
Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis.J. Pathol. 2008-11-01;216(3):317-27.
Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Biochim. Biophys. Acta 2008-11-01;1783(11):2145-54.
Ribavirin targets eIF4E dependent Akt survival signaling.Biochem. Biophys. Res. Commun. 2008-10-24;375(3):341-5.
Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia.Oncogene 2008-10-23;27(49):6356-64.
C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division.Dev. Biol. 2008-09-15;321(2):368-78.
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.Curr. Biol. 2008-09-09;18(17):1269-77.