IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration.Proc. Natl. Acad. Sci. U.S.A. 2010-12-28;107(52):22558-63.
Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytes.J. Cell Biol. 2010-12-27;191(7):1351-65.
A comprehensive map of the mTOR signaling network.Mol. Syst. Biol. 2010-12-21;6:453.
When enough is enough: detrimental effects of excess histones.Cell Cycle 2010-12-15;9(24):4783.
Multiplexing of multicolor bioluminescence resonance energy transfer.Biophys. J. 2010-12-15;99(12):4037-46.
Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease.Blood 2010-12-02;116(23):4859-69.
[The greater RTK/RAS/ERK signalling pathway: how genetics has helped piece together a signalling network].Med Sci (Paris) 2010-12-01;26(12):1067-73.
[mTOR, the mammalian target of rapamycin].Med Sci (Paris) 2010-12-01;26(12):1056-60.
A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A.Nat. Cell Biol. 2010-12-01;12(12):1186-93.
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.EMBO J. 2010-12-01;29(23):3939-51.