IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.Proc. Natl. Acad. Sci. U.S.A. 2013-12-24;110(52):E5088-97.
The Coming of Age of Phosphoproteomics--from Large Data Sets to Inference of Protein Functions.Mol. Cell Proteomics 2013-12-01;12(12):3453-64.
Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and Intralipid solutions and correlation to insulin levels.Metab. Clin. Exp. 2013-12-01;62(12):1850-7.
Cell cortex composition and homeostasis resolved by integrating proteomics and quantitative imaging.Cytoskeleton (Hoboken) 2013-11-01;70(11):741-54.
A host YB-1 ribonucleoprotein complex is hijacked by hepatitis C virus for the control of NS3-dependent particle production.J. Virol. 2013-11-01;87(21):11704-20.
Regulation of Stress-Inducible Phosphoprotein 1 Nuclear Retention by Protein Inhibitor of Activated STAT PIAS1.Mol. Cell Proteomics 2013-11-01;12(11):3253-70.
Disruption of TBC1D7, a subunit of the TSC1-TSC2 protein complex, in intellectual disability and megalencephaly.J. Med. Genet. 2013-11-01;50(11):740-4.
Funding considerations for the disclosure of genetic incidental findings in biobank research.Clin. Genet. 2013-11-01;84(5):397-406.
Insulin Activates RSK (p90 Ribosomal S6 Kinase) to Trigger a New Negative Feedback Loop That Regulates Insulin Signaling for Glucose Metabolism.J. Biol. Chem. 2013-10-25;288(43):31165-76.
Rapamycin Resistance: mTORC1 Substrates Hold Some of the Answers.Curr. Biol. 2013-10-07;23(19):R880-3.