IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Development and Characterization of Pepducins as Gs-biased Allosteric Agonists.J. Biol. Chem. 2014-12-26;289(52):35668-84.
SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells.PLoS Genet. 2014-12-18;10(12):e1004768.
When Will Resistance Be Futile?Cancer Res. 2014-12-15;74(24):7175-7180.
Bloody signals: From birth to disease and death.Exp. Hematol. 2014-12-01;42(12):989-94.
The yeast polo kinase cdc5 regulates the shape of the mitotic nucleus.Curr. Biol. 2014-12-01;24(23):2861-7.
Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1.Br. J. Pharmacol. 2014-12-01;171(23):5265-79.
Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation.DNA Repair (Amst.) 2014-11-24;25C:54-59.
Proteomic-Coupled-Network Analysis of T877A-Androgen Receptor Interactomes Can Predict Clinical Prostate Cancer Outcomes between White (Non-Hispanic) and African-American Groups.PLoS ONE 2014-11-19;9(11):e113190.
MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.Nat Commun 2014-11-18;5:5413.
Targeted protein degradation as a tumor suppressor.Cell Cycle 2014-11-15;13(22):3473.