IRIC discoveries have spurred major advances in understanding the development of cancer and opened the way to the creation of new, more targeted therapeutic solutions. Its publications are a reflection of these accomplishments. They also demonstrate the Institute’s drive and productivity.
Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning.Cell Syst 2015-12-23;1(6):383-95.
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection.Sci Transl Med 2015-12-16;7(318):318ra200.
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.Bioorg. Med. Chem. 2015-12-15;23(24):7597-606.
DAF-18/PTEN locally antagonizes insulin signalling to couple germline stem cell proliferation to oocyte needs in C. elegans.Development 2015-12-15;142(24):4230-41.
The experimental power of FR900359 to study Gq-regulated biological processes.Nat Commun 2015-12-14;6:10156.
The lighthouse at the end of the chromosome.F1000Res 2015-12-11;4.
Enhancement of mass spectrometry performance for proteomic analyses using high-field asymmetric waveform ion mobility spectrometry (FAIMS).J Mass Spectrom 2015-11-01;50(11):1181-95.
Discovery of protein acetylation patterns by deconvolution of peptide isomer mass spectra.Nat Commun 2015-10-15;6:8648.