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  • June 15, 2023

    CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling.

    Serwe G, Kachaner D, Gagnon J, Plutoni C, Lajoie D, Duramé E, Sahmi M, Garrido D, Lefrançois M, Arseneault G, Saba-El-Leil MK, Meloche S, Emery G, Therrien M
    Nat Commun 2023-06-15 ;14( 1 ):3560

  • June 13, 2023

    HER2∆16 Engages ENPP1 To Promote an Immune Cold Microenvironment in Breast Cancer.

    Attalla SS, Boucher J, Proud H, Taifour T, Zuo D, Sanguin-Gendreau V, Ling C, Johnson G, Li V, Luo RB, Kuasne H, Papavasiliou V, Walsh LA, Barok M, Joensuu H, Park M, Roux PP, Muller WJ
    Cancer Immunol Res 2023-06-13 ;

  • May 31, 2023

    In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer.

    Dervovic D, Malik AA, Chen ELY, Narimatsu M, Adler N, Afiuni-Zadeh S, Krenbek D, Martinez S, Tsai R, Boucher J, Berman JM, Teng K, Ayyaz A, Lü Y, Mbamalu G, Loganathan SK, Lee J, Zhang L, Guidos C, Wrana J, Valipour A, Roux PP, Reimand J, Jackson HW, Schramek D
    Nat Commun 2023-05-31 ;14( 1 ):3150

  • May 30, 2023

    Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation.

    Trinh VQ, Lee TF, Lemoinne S, Ray KC, Ybanez MD, Tsuchida T, Carter JK, Agudo J, Brown BD, Akat KM, Friedman SL, Lee YA
    Sci Signal 2023-05-30 ;16( 787 ):eadf6696

  • May 19, 2023

    Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen.

    Pelletier B, Duhamel S, Tambutet G, Jarvis S, Cléroux P, David M, Tanguay PL, Voisin L, James C, Lavoie R, Gareau Y, Flynn-Robitaille J, Lorca T, Ruel R, Marinier A, Meloche S
    ACS Chem Biol 2023-05-19 ;18( 5 ):1039-1046

  • May 9, 2023

    Towards clinically meaningful expansion of human HSCs.

    Tellechea MF, Chagraoui J, Cohen S, Sauvageau G
    Cell Res 2023-05-09 ;

  • May 4, 2023

    K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ).

    Suresh HG, Bonneil E, Albert B, Dominique C, Costanzo M, Pons C, David Masinas MP, Shuteriqi E, Shore D, Henras AK, Thibault P, Boone C, Andrews BJ
    bioRxiv 2023-05-04 ;

  • May 2, 2023

    Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1.

    Chalkiadaki K, Hooshmandi M, Lach G, Statoulla E, Simbriger K, Amorim IS, Kouloulia S, Zafeiri M, Pothos P, Bonneil E, Gantois I, Popic J, Kim SH, Wong C, Cao R, Komiyama NH, Atlasi Y, Jafarnejad SM, Khoutorsky A, Gkogkas CG
    Brain 2023-05-02 ;146( 5 ):2175-2190

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