Latest publications
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November 1, 2021 Paradoxical implication of BAX/BAK in the persistence of tetraploid cells.
Deng J, Gutiérrez LG, Stoll G, Motiño O, Martins I, Núñez L, Bravo-San Pedro JM, Humeau J, Bordenave C, Pan J, Fohrer-Ting H, Souquere S, Pierron G, Hetz C, Villalobos C, Kroemer G, Senovilla L
Cell Death Dis 2021-11-01 ;12( 11 ):1039 -
October 29, 2021 Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.
St-Cyr D, Ceccarelli DF, Orlicky S, van der Sloot AM, Tang X, Kelso S, Moore S, James C, Posternak G, Coulombe-Huntington J, Bertomeu T, Marinier A, Sicheri F, Tyers M
Sci Adv 2021-10-29 ;7( 44 ):eabi5797 -
October 22, 2021 CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.
Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon E, Lemieux S, Perreault C
PLoS Comput Biol 2021-10-22 ;17( 10 ):e1009482 -
October 16, 2021 Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
Saraon P, Snider J, Schormann W, Rai A, Radulovich N, Sánchez-Osuna M, Coulombe-Huntington J, Huard C, Mohammed M, Lima-Fernandes E, Thériault B, Halabelian L, Chan M, Joshi D, Drecun L, Yao Z, Pathmanathan S, Wong V, Lyakisheva A, Aboualizadeh F, Niu L, Li F, Kiyota T, Subramanian R, Joseph B, Aman A, Prakesch M, Isaac M, Mamai A, Poda G, Vedadi M, Marcellus R, Uehling D, Leighl N, Sacher A, Samaržija M, Jakopović M, Arrowsmith C, Tyers M, Tsao MS, Andrews D, Al-Awar R, Stagljar I
J Mol Biol 2021-10-16 ;433( 23 ):167294