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  • November 1, 2017

    PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.

    Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP
    Mol. Cancer Ther. 2017-11-01 ;16( 11 ):2528-2542

  • November 1, 2017

    UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis.

    Aucagne R, Girard S, Mayotte N, Lehnertz B, Lopes-Paciencia S, Gendron P, Boucher G, Chagraoui J, Sauvageau G
    FASEB J. 2017-11-01 ;31( 11 ):5012-5018

  • October 31, 2017

    RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition.

    Jin T, Lavoie H, Sahmi M, David M, Hilt C, Hammell A, Therrien M
    Nat Commun 2017-10-31 ;8( 1 ):1211

  • October 24, 2017

    Mass Cytometric Analysis Reveals Viable Activated Caspase-3+ Luminal Progenitors in the Normal Adult Human Mammary Gland.

    Knapp D, Kannan N, Pellacani D, Eaves CJ
    Cell Rep 2017-10-24 ;21( 4 ):1116-1126

  • October 23, 2017

    Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.

    Smith M, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M
    Nat Commun 2017-10-23 ;8( 1 ):1099

  • October 17, 2017

    Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.

    Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, Yi S
    Cell Rep 2017-10-17 ;21( 3 ):798-812

  • September 19, 2017

    HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma.

    Matsuda H, Campion CG, Fujiwara K, Ikeda J, Cossette S, Verissimo T, Ogasawara M, Gaboury L, Saito K, Yamaguchi K, Takahashi S, Endo M, Fukuda N, Soma M, Hamet P, Tremblay J
    Oncotarget 2017-09-19 ;8( 41 ):69559-69576

  • September 19, 2017

    Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy.

    Teixeira LB, Parreiras-E-Silva LT, Bruder-Nascimento T, Duarte DA, Simões SC, Costa RM, Rodríguez DY, Ferreira PAB, Silva CAA, Abrao EP, Oliveira EB, Bouvier M, Tostes RC, Costa-Neto CM
    Sci Rep 2017-09-19 ;7( 1 ):11903

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