94 results
IL-15 Prevents the Development of T-ALL from Aberrant Thymocytes with Impaired DNA Repair Functions and Increased NOTCH1 Activation.
Nandi M, Ghosh A, Akbari SA, Bobbala D, Boucher MJ, Menendez A, Hoang T, Ilangumaran S, Ramanathan S
Cancers (Basel)
2023-01-21
;15(
3
):.
PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.
Zhao X, Bartholdy B, Yamamoto Y, Evans EK, Alberich-Jordà M, Staber PB, Benoukraf T, Zhang P, Zhang J, Trinh BQ, Crispino JD, Hoang T, Bassal MA, Tenen DG
Commun Biol
2022-09-14
;5(
1
):961.
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.
Baran N, Lodi A, Dhungana Y, Herbrich S, Collins M, Sweeney S, Pandey R, Skwarska A, Patel S, Tremblay M, Kuruvilla VM, Cavazos A, Kaplan M, Warmoes MO, Veiga DT, Furudate K, Rojas-Sutterin S, Haman A, Gareau Y, Marinier A, Ma H, Harutyunyan K, Daher M, Garcia LM, Al-Atrash G, Piya S, Ruvolo V, Yang W, Shanmugavelandy SS, Feng N, Gay J, Du D, Yang JJ, Hoff FW, Kaminski M, Tomczak K, Eric Davis R, Herranz D, Ferrando A, Jabbour EJ, Emilia Di Francesco M, Teachey DT, Horton TM, Kornblau S, Rezvani K, Sauvageau G, Gagea M, Andreeff M, Takahashi K, Marszalek JR, Lorenzi PL, Yu J, Tiziani S, Hoang T, Konopleva M
Nat Commun
2022-05-19
;13(
1
):2801.
Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia.
Veiga DFT, Tremblay M, Gerby B, Herblot S, Haman A, Gendron P, Lemieux S, Zúñiga-Pflücker JC, Hébert J, Cohen JP, Hoang T
Front Immunol
2022-01-01
;13:867443.
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, Salameh S, Hoang T, Jackson AP, Brown GW, Charron F
Nature Cancer
2020-07-20
;1(
8
):840-854.
A targetable cue in T-cell malignancy.
Gerby B, Hoang T
Blood
2020-05-07
;135(
19
):1616-1617.
Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.
Da Costa EM, Armaos G, McInnes G, Beaudry A, Moquin-Beaudry G, Bertrand-Lehouillier V, Caron M, Richer C, St-Onge P, Johnson JR, Krogan N, Sai Y, Downey M, Rafei M, Boileau M, Eppert K, Flores-Díaz E, Haman A, Hoang T, Sinnett D, Beauséjour C, McGraw S, Raynal NJ
J. Exp. Clin. Cancer Res.
2019-06-13
;38(
1
):251.
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, Schneider P, Hoang T, Allam R
J. Clin. Invest.
2018-04-02
;128(
4
):1597-1614.
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith M, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M
Nat Commun
2017-10-23
;8(
1
):1099.
Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP
Mol. Cell. Biol.
2017-04-01
;37(
7
):.
High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.
Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok B, Roux PP, Hoang T
J. Clin. Invest.
2016-12-01
;126(
12
):4569-4584.
Myelopoiesis.
Lessard J, Hoang T
Encyclopedia of Immunobiology
2016-04-27
;1:26-37.
SCL/TAL1 in Hematopoiesis and Cellular Reprogramming.
Hoang T, Lambert JA, Martin R
Curr. Top. Dev. Biol.
2016-02-18
;118:163-204.
The LMO2 oncogene regulates DNA replication in hematopoietic cells.
Sincennes MC, Humbert M, Grondin B, Lisi V, Veiga DF, Haman A, Cazaux C, Mashtalir N, Affar el B, Verreault A, Hoang T
Proc. Natl. Acad. Sci. U.S.A.
2016-02-02
;113(
5
):1393-8.
SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells.
Gerby B, Tremblay CS, Tremblay M, Rojas-Sutterlin S, Herblot S, Hébert J, Sauvageau G, Lemieux S, Lécuyer E, Veiga DF, Hoang T
PLoS Genet.
2014-12-18
;10(
12
):e1004768.
LMO1/2 regulates DNA replication in hematopoietic cells.
Humbert M, Sincennes MC, Grondin B, Haman A, Tremblay M, Verreault A, Hoang T
Exp. Hematol.
2014-08-01
;42(
8 Suppl
):S19.
Oncogenic transcription factors, from hematopoietic stem cells to thymocyte reprogramming.
Hoang T
Exp. Hematol.
2014-08-01
;42(
8 Suppl
):S11.
Self-renewal network activated by SCL-LMO1 confer aberrant stem cell properties to immature thymocytes.
Veiga D, Gerby B, Hoang T
Exp. Hematol.
2014-08-01
;42(
8 Suppl
):S64.
Kit and Scl regulation of hematopoietic stem cells.
Rojas-Sutterlin S, Lecuyer E, Hoang T
Curr. Opin. Hematol.
2014-07-01
;21(
4
):256-264.
Genetic interaction between Kit and Scl.
Lacombe J, Krosl G, Tremblay M, Gerby B, Martin R, Aplan PD, Lemieux S, Hoang T
Blood
2013-08-15
;122(
7
):1150-61.
RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells.
Girard N, Tremblay M, Humbert M, Grondin B, Haman A, Labrecque J, Chen B, Chen Z, Chen SJ, Hoang T
Proc. Natl. Acad. Sci. U.S.A.
2013-08-13
;110(
33
):13522-7.
Modelling acute leukemias in mice: clonal evolution and the emergence of leukemic stem cells.
Gerby B, Hoang T
BMC Proc
2013-04-04
;7(
Suppl 2 Sao Paulo Advanced School of Comparative Oncology: AbstractsClaudia Aparecida Rainho, Patricia Pintor dos Reis and Silvia Regina RogattoPublication of this supplement was funded by the Sao Paulo Research Foundation (FAPESP)
):K1.
Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.
Carbonneau CL, Despars G, Rojas-Sutterlin S, Fortin A, Le O, Hoang T, Beauséjour CM
Blood
2012-01-19
;119(
3
):717-26.
The T-ALL paradox in cancer.
Hoang T, Hoang T
Nat. Med.
2010-11-01
;16(
11
):1185-6.
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.
Tremblay M, Tremblay CS, Herblot S, Aplan PD, Hébert J, Perreault C, Hoang T
Genes Dev.
2010-06-01
;24(
11
):1093-105.
Of mice and men: how an oncogene transgresses the limits and predisposes to T cell acute lymphoblastic leukemia.
Hoang T
Sci Transl Med
2010-03-03
;2(
21
):21ps10.
Scl regulates the quiescence and the long-term competence of hematopoietic stem cells.
Lacombe J, Herblot S, Rojas-Sutterlin S, Haman A, Barakat S, Iscove NN, Sauvageau G, Hoang T
Blood
2010-01-28
;115(
4
):792-803.
Early T cell differentiation lessons from T-cell acute lymphoblastic leukemia.
Tremblay CS, Hoang T, Hoang T
Prog Mol Biol Transl Sci
2010-01-01
;92:121-56.
Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.
Topisirovic I, Siddiqui N, Orolicki S, Skrabanek LA, Tremblay M, Hoang T, Borden K
Mol. Cell. Biol.
2009-03-01
;29(
5
):1152-62.
Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction.
Lécuyer E, Larivière S, Sincennes MC, Haman A, Lahlil R, Todorova M, Tremblay M, Wilkes BC, Hoang T
J. Biol. Chem.
2007-11-16
;282(
46
):33649-58.
c-Jun homodimers can function as a context-specific coactivator.
Grondin B, Lefrancois M, Tremblay M, Saint-Denis M, Haman A, Waga K, Bédard A, Tenen DG, Hoang T
Mol. Cell. Biol.
2007-04-01
;27(
8
):2919-33.
Novel insights into the pathogenesis of the Graffi murine leukemia retrovirus.
Voisin V, Barat C, Hoang T, Rassart E
J. Virol.
2006-04-01
;80(
8
):4026-37.
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.
Goardon N, Lambert JA, Rodriguez P, Nissaire P, Herblot S, Thibault P, Dumenil D, Strouboulis J, Romeo PH, Hoang T
EMBO J.
2006-01-25
;25(
2
):357-66.
The origin of hematopoietic cell type diversity.
Hoang T
Oncogene
2004-09-20
;23(
43
):7188-98.
Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia.
Ferrando AA, Herblot S, Palomero T, Hansen M, Hoang T, Fox EA, Look AT
Blood
2004-03-01
;103(
5
):1909-11.
SCL assembles a multifactorial complex that determines glycophorin A expression.
Lahlil R, Lécuyer E, Herblot S, Hoang T
Mol. Cell. Biol.
2004-02-01
;24(
4
):1439-52.
SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis.
Martin R, Lahlil R, Damert A, Miquerol L, Nagy A, Keller G, Hoang T
Development
2004-02-01
;131(
3
):693-702.
SCL: from the origin of hematopoiesis to stem cells and leukemia.
Lécuyer E, Hoang T
Exp. Hematol.
2004-01-01
;32(
1
):11-24.
Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis.
Levantini E, Giorgetti A, Cerisoli F, Traggiai E, Guidi A, Martin R, Acampora D, Aplan PD, Keller G, Simeone A, Iscove NN, Hoang T, Magli MC
Proc. Natl. Acad. Sci. U.S.A.
2003-09-02
;100(
18
):10299-303.
Translational control of SCL-isoform expression in hematopoietic lineage choice.
Calkhoven CF, Muller C, Martin R, Krosl G, Pietsch H, Hoang T, Leutz A
Genes Dev.
2003-04-15
;17(
8
):959-64.
Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL.
Tremblay M, Herblot S, Lecuyer E, Hoang T
J. Biol. Chem.
2003-04-11
;278(
15
):12680-7.
Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment.
Doan LL, Kitay MK, Yu Q, Singer A, Herblot S, Hoang T, Bear SE, Morse HC, Tsichlis PN, Grimes HL
J. Immunol.
2003-03-01
;170(
5
):2356-66.
The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1.
Lécuyer E, Herblot S, Saint-Denis M, Martin R, Begley CG, Porcher C, Orkin SH, Hoang T
Blood
2002-10-01
;100(
7
):2430-40.
Gradient of E2A activity in B-cell development.
Herblot S, Aplan PD, Hoang T
Mol. Cell. Biol.
2002-02-01
;22(
3
):886-900.
Neutrophils at the cross roads of cytokine and RA receptors. Commentary for plenary paper.
Hoang T
Blood
2002-01-01
;99:729.
Implication of tyrosine kinase receptor and steel factor in cell density-dependent growth in cervical cancers and leukemias.
Caceres-Cortes JR, Alvarado-Moreno JA, Waga K, Rangel-Corona R, Monroy-Garcia A, Rocha-Zavaleta L, Urdiales-Ramos J, Weiss-Steider B, Haman A, Hugo P, Brousseau R, Hoang T
Cancer Res.
2001-08-15
;61(
16
):6281-9.
Steel factor sustains SCL expression and the survival of purified CD34+ bone marrow cells in the absence of detectable cell differentiation.
Caceres-Cortes JR, Krosl G, Tessier N, Hugo P, Hoang T
Stem Cells
2001-01-01
;19(
1
):59-70.
SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression.
Herblot S, Steff AM, Hugo P, Aplan PD, Hoang T
Nat. Immunol.
2000-08-01
;1(
2
):138-44.
A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts.
Vitelli L, Condorelli G, Lulli V, Hoang T, Luchetti L, Croce CM, Peschle C
Mol. Cell. Biol.
2000-07-01
;20(
14
):5330-42.
Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly.
Haman A, Cadieux C, Wilkes B, Hercus T, Lopez A, Clark S, Hoang T
J. Biol. Chem.
1999-11-26
;274(
48
):34155-63.