Publications

A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens.Baccelli I, Krosl J, Boucher G, Boivin I, Lavallée VP, Hébert J, Lemieux S, Marinier A, Sauvageau GBlood Cancer J 2017-02-17;7(2):e529.

Distinct signaling programs control human hematopoietic stem cell survival and proliferation.Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, Eaves CJBlood 2017-01-19;129(3):307-318.

Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila.Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien MDev. Biol. 2017-01-01;421(1):16-26.

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok BH, Roux PP, Hoang TJ. Clin. Invest. 2016-12-01;126(12):4569-4584.

Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers.Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault CSci Rep 2016-09-23;6:34019.

Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations.Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Girard S, Hébert J, Sauvageau GLeukemia 2016-07-01;30(7):1621-4.

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors.Lavallée VP, Krosl J, Lemieux S, Boucher G, Gendron P, Pabst C, Boivin I, Marinier A, Guidos CJ, Meloche S, Hébert J, Sauvageau GBlood 2016-06-16;127(24):3054-61.

Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets.Maiga A, Lemieux S, Pabst C, Lavallée VP, Bouvier M, Sauvageau G, Hébert JBlood Cancer J 2016-06-03;6(6):e431.

RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature.Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Armstrong RN, Sauvageau G, Hébert JBlood 2016-05-19;127(20):2498-501.

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, Humphries K, Lemieux S, Hébert J, Sauvageau G, Barabé FBlood 2016-04-21;127(16):2018-27.

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