Understanding the protective role of the immune system against cancers and development of immuno-therapeutic approaches. Characterization of the blood stem cells and their derivatives and study of the genesis of hematological cancers.
Principal Investigators
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Katherine Borden
Structure and Function of the Cell Nucleus
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Etienne Gagnon
Cancer Immunobiology
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Trang Hoang
Hematopoiesis and Leukemia
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David Knapp
Cellular Engineering
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Philippe P. Roux
Cell Signaling and Proteomics
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Claude Perreault
Immunobiology
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Brian Wilhelm
High-Throughput Genomics
Publications
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March 23, 2023 Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine.
Assouline S, Gasiorek J, Bergeron J, Lambert C, Culjkovic-Kraljacic B, Cocolakis E, Zakaria C, Szlachtycz D, Yee K, Borden K
Haematologica 2023-03-23 ; -
March 21, 2023 Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.
Millar DG, Yang SYC, Sayad A, Zhao Q, Nguyen LT, Warner K, Sangster AG, Nakatsugawa M, Murata K, Wang BX, Shaw P, Clarke B, Bernardini MQ, Pugh T, Thibault P, Hirano N, Perreault C, Ohashi PS
Cancer Immunol Immunother 2023-03-21 ; - See all publications