Understanding the protective role of the immune system against cancers and development of immuno-therapeutic approaches. Characterization of the blood stem cells and their derivatives and study of the genesis of hematological cancers.
Principal Investigators
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Katherine Borden
Structure and Function of the Cell Nucleus
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Etienne Gagnon
Cancer Immunobiology
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Trang Hoang
Hematopoiesis and Leukemia
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David Knapp
Cellular Engineering
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Philippe P. Roux
Cell Signaling and Proteomics
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Claude Perreault
Immunobiology
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Brian Wilhelm
High-Throughput Genomics
Publications
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September 20, 2023 CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
Blood Adv 2023-09-20 ; -
August 28, 2023 GPRC5C Drives Branched-Chain Amino Acid Metabolism in Leukemogenesis.
Zhang YW, Velasco-Hernandez T, Mess J, Lalioti ME, Romero-Mulero MC, Obier N, Karantzelis N, Rettkowski J, Schönberger K, Karabacz N, Jäcklein K, Morishima T, Trincado JL, Romecin P, Martinez-Moreno A, Takizawa H, Shoumariyeh K, Renders S, Zeiser R, Pahl HL, Béliveau F, Hébert J, Lehnertz B, Sauvageau G, Menendez P, Cabezas-Wallscheid N
Blood Adv 2023-08-28 ; -
August 15, 2023 - See all publications