Research field

Immunology & Hematopoiesis

Understanding the protective role of the immune system against cancers and development of immuno-therapeutic approaches. Characterization of the blood stem cells and their derivatives and study of the genesis of hematological cancers.

Principal Investigators

  • Katherine Borden

    Structure and Function of the Cell Nucleus

  • Trang Hoang

    Hematopoiesis and Leukemia

  • Julie Lessard

    Chromatin Structure and Stem Cell Biology

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Guy Sauvageau

    Molecular Genetics of Stem Cells

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • octobre 1, 2020

    Major multilevel molecular divergence between THP-1 cells from different biorepositories.

    Noronha N, Ehx G, Meunier MC, Laverdure JP, Thériault C, Perreault C
    Int. J. Cancer 2020-10-01 ;147( 7 ):2000-2006.

  • septembre 1, 2020

    IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.

    Benhammadi M, Mathé J, Dumont-Lagacé M, Kobayashi KS, Gaboury L, Brochu S, Perreault C
    J. Immunol. 2020-09-01 ;205( 5 ):1268-1280.

  • août 18, 2020

    An ErbB2 splice variant lacking exon 16 drives lung carcinoma.

    Smith HW, Yang L, Ling C, Walsh A, Martinez VD, Boucher J, Zuo D, Sokol ES, Pavlick DC, Frampton GM, Chmielecki J, Jones LM, Roux PP, Lockwood WW, Muller WJ
    Proc. Natl. Acad. Sci. U.S.A. 2020-08-18 ;117( 33 ):20139-20148.

  • See all publications