Principal Investigator

Marc Therrien

Intracellular Signalling

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Marc Therrien is a full professor in the Department of Pathology and Cell Biology at the Faculty of Medicine of the Université de Montréal and Chief Officer of IRIC.

His work on gene transcription control under Jacques Drouin at the Montreal Clinical Research Institute (IRCM) led to a PhD in biochemistry from UdeM in 1993.

He then completed a postdoctoral fellowship in molecular genetics with Gerald M. Rubin at the University of California, Berkeley, where he identified several novel components of the RAS-MAPK signaling pathway, whose deregulation is closely linked to the development of many cancers.

Returning to Montreal in 1999, he became a senior researcher at the IRCM. In 2003, he joined the Institute for Research in Immunology and Cancer (IRIC) at UdeM, of which he is a founding member, and became head of the Intracellular Signaling Research Unit. He also holds a Canada Research Chair in Intracellular Signaling.

In 2013, he was appointed Scientific Director of IRIC, a position he held for ten years. In 2024, he became Executive Director of the Institute, succeeding Michel Bouvier.

Chief Executive Officer, IRIC

Principal Investigator, Intracellular Signalling Research Unit, IRIC

Professor, Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal

Research unit on intracellular signalling

Marcelle-Coutu Pavilion, 1306-3 (2306-3)

Phone (office)
(514) 343-7837
Fax
(514) 343-7780
Email
marc.therrien@umontreal.ca

Intracellular Signalling

Marc Therrien and his team study the signalling mechanisms involved in cell proliferation and differentiation, more specifically those of the RAS-MAPK intracellular pathway. Dysregulation of these mechanisms is the basis for a large number of cancers.

Research topics

Publications

Awards and distinctions

  • Canada Research Chair, Tier 1, 2017-2022

  • Canada Research Chair, Tier 2, 2009-2014

  • Canada Research Chair, Tier 2, 2004-2009

  • Scholarship, Canadian Institutes of Health Research, 1999-2004

  • Chercheur-boursier (junior I), FRSQ (declined), 1999-2001

  • Centennial Fellowship, Medical Research Council of Canada, 1996-1998

  • Post-doctoral Fellowship, National Cancer Institute of Canada, 1993-1996

  • Post-doctoral Fellowship, Medical Research Council of Canada (declined), 1993-1994

  • Studentship, Medical Research Council of Canada, 1987-1992

  • Studentship, FCAR (Training funds agency, Quebec), 1986-1987

  • See all awards