Research field

Cell Signaling & Protein Dynamics

Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Gregory Emery

    Vesicular Trafficking and Cell Signalling

  • Benjamin Kwok

    Chemical Biology of Cell Division

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • December 23, 2020

    How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling.

    Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO
    Cell 2020-12-23 ;183( 7 ):1813-1825.e18.

  • December 22, 2020

    Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor.

    Trân K, Murza A, Sainsily X, Delile E, Couvineau P, Côté J, Coquerel D, Peloquin M, Auger-Messier M, Bouvier M, Lesur O, Sarret P, Marsault E
    J Med Chem 2020-12-22 ;.

  • December 8, 2020

    Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands - Functional characterization and modeling studies on H3 and H4 receptors.

    Corrêa MF, Balico-Silva AL, Kiss DJ, Fernandes GAB, Maraschin JC, Parreiras-E-Silva LT, Varela MT, Simões SC, Bouvier M, Keserű GM, Costa-Neto CM, Fernandes JPS
    Bioorg Med Chem 2020-12-08 ;30:115924.

  • See all publications