Research field

Cell Signaling & Protein Dynamics

Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Gregory Emery

    Vesicular Trafficking and Cell Signalling

  • Benjamin Kwok

    Chemical Biology of Cell Division

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • July 2, 2022

    Michaelis-Menten quantification of ligand signalling bias applied to the promiscuous Vasopressin V2 receptor.

    Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D
    Mol Pharmacol 2022-07-02 ;.

  • July 1, 2022

    Community guidelines for GPCR ligand bias: IUPHAR review 32.

    Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov KA, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, Shukla AK, Sommer ME, Gloriam DE
    Br J Pharmacol 2022-07-01 ;179( 14 ):3651-3674.

  • June 28, 2022

    CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells.

    Ansari U, Tomellini E, Chagraoui J, Lehnertz B, Mayotte N, Bordeleau ME, Roux PP, Sauvageau G
    Blood Adv 2022-06-28 ;6( 12 ):3626-3631.

  • See all publications