Research field

Cell Signaling & Protein Dynamics

Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Gregory Emery

    Vesicular Trafficking and Cell Signalling

  • Benjamin Kwok

    Chemical Biology of Cell Division

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • November 11, 2019

    Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation.

    Coutinho de Oliveira L, Volpon L, Rahardjo AK, Osborne MJ, Culjkovic-Kraljacic B, Trahan C, Oeffinger M, Kwok B, Borden K
    Proc. Natl. Acad. Sci. U.S.A. 2019-11-11 ;.

  • October 1, 2019

    Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children.

    de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL
    Genes Chromosomes Cancer 2019-10-01 ;58( 10 ):723-730.

  • September 17, 2019

    The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge.

    Zeledon C, Sun X, Plutoni C, Emery G
    Cell Rep 2019-09-17 ;28( 12 ):3238-3248.e3.

  • See all publications