Research field

Cell Signaling & Protein Dynamics

Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Gregory Emery

    Vesicular Trafficking and Cell Signalling

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • November 18, 2022

    Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration.

    Tran V, Nahlé S, Robert A, Desanlis I, Killoran R, Ehresmann S, Thibault MP, Barford D, Ravichandran KS, Sauvageau M, Smith M, Kmita M, Côté JF
    Nat Commun 2022-11-18 ;13( 1 ):7077

  • November 15, 2022

    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool.

    Sénéchal C, Fujita R, Jamet S, Maiga A, Dort J, Orfi Z, Dumont NA, Bouvier M, Crist C
    Cell Rep 2022-11-15 ;41( 7 ):111645

  • November 11, 2022

    Computationally designed GPCR quaternary structures bias signaling pathway activation.

    Paradis JS, Feng X, Murat B, Jefferson RE, Sokrat B, Szpakowska M, Hogue M, Bergkamp ND, Heydenreich FM, Smit MJ, Chevigné A, Bouvier M, Barth P
    Nat Commun 2022-11-11 ;13( 1 ):6826

  • See all publications