Development of informatics tools for the analysis and interpretation of large biological datasets including genomics, proteomics and structural biology data. Modeling of complex biological systems.
Principal Investigators
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Delphine Bouilly
Design and Application of Electronic Nanobiosensors
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Michel Bouvier
Molecular Pharmacology
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Louis Gaboury
Histology and Molecular Pathology
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Jean-Claude Labbé
Cell Division and Differentiation
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Sébastien Lemieux
Functional and Structural Bioinformatics
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Anne Marinier
Drug Discovery Unit
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Michael Tyers
Systems Biology and Synthetic Biology
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Brian Wilhelm
High-Throughput Genomics
Publications
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December 23, 2019 Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways.
Hill S, Reichermeier K, Scott DC, Samentar L, Coulombe-Huntington J, Izzi L, Tang X, Ibarra R, Bertomeu T, Moradian A, Sweredoski MJ, Caberoy N, Schulman BA, Sicheri F, Tyers M, Kleiger G
Elife 2019-12-23 ;8:. -
December 3, 2019 Cryptic recurrent ACIN1-NUTM1 fusions in non-KMT2A-rearranged infant acute lymphoblastic leukemia.
Pincez T, Landry JR, Roussy M, Jouan L, Bilodeau M, Laramée L, Couture F, Sinnett D, Gendron P, Hébert J, Oligny L, Rouette A, Tran TH, Wilhelm B, Bittencourt H, Cellot S
Genes Chromosomes Cancer 2019-12-03 ;59( 2 ):125-130. -
November 20, 2019 Axillary Lymph Node Ultrasound Following Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer: Results from the SN FNAC Study.
Morency D, Dumitra S, Parvez E, Martel K, Basik M, Robidoux A, Poirier B, Holloway CMB, Gaboury L, Sideris L, Meterissian S, Boileau JF
Ann. Surg. Oncol. 2019-11-20 ;26( 13 ):4337-4345. - See all publications