Research field

Computational Analysis & Modeling

Development of informatics tools for the analysis and interpretation of large biological datasets including genomics, proteomics and structural biology data. Modeling of complex biological systems.

Principal Investigators

  • Delphine Bouilly

    Design and Application of Electronic Nanobiosensors

  • Louis Gaboury

    Histology and Molecular Pathology

  • Jean-Claude Labbé

    Cell Division and Differentiation

  • Sébastien Lemieux

    Functional and Structural Bioinformatics

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Michael Tyers

    Systems Biology and Synthetic Biology

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • October 3, 2022

    New oral protease-activated receptor 4 antagonist BMS-986120: tolerability, pharmacokinetics, pharmacodynamics, and gene variant effects in humans.

    Merali S, Wang Z, Frost C, Callejo M, Hedrick M, Hui L, Meadows Shropshire S, Xu K, Bouvier M, DeSouza MM, Yang J
    Platelets 2022-10-03 ;33( 7 ):969-978.

  • September 13, 2022

    Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia.

    Lisi V, Blanchard E, Vladovsky M, Audemard E, Ferghaly A, Lemieux S, Hébert J, Sauvageau G, Lavallée VP
    Blood Adv 2022-09-13 ;6( 17 ):5160-5164.

  • September 6, 2022

    Proteogenomics and Differential Ion Mobility Enable the Exploration of the Mutational Landscape in Colon Cancer Cells.

    Wu Z, Bonneil E, Belford M, Boeser C, Ruiz Cuevas MV, Lemieux S, Dunyach JJ, Thibault P
    Anal Chem 2022-09-06 ;94( 35 ):12086-12094.

  • See all publications