Development of informatics tools for the analysis and interpretation of large biological datasets including genomics, proteomics and structural biology data. Modeling of complex biological systems.
Principal Investigators
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Delphine Bouilly
Design and Application of Electronic Nanobiosensors
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Michel Bouvier
Molecular Pharmacology
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Louis Gaboury
Histology and Molecular Pathology
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Jean-Claude Labbé
Cell Division and Differentiation
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Sébastien Lemieux
Functional and Structural Bioinformatics
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Anne Marinier
Medicinal Chemistry
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Michael Tyers
Systems Biology and Synthetic Biology
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Brian Wilhelm
High-Throughput Genomics
Publications
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September 12, 2019 Cryptic recurrent ACIN1-NUTM1 fusions in non KMT2A-rearranged infant acute lymphoblastic leukemia.
Pincez T, Landry JR, Roussy M, Jouan L, Bilodeau M, Laramée L, Couture F, Sinnett D, Gendron P, Hébert J, Oligny L, Rouette A, Tran TH, Wilhelm B, Bittencourt H, Cellot S
Genes Chromosomes Cancer 2019-09-12 ;. -
August 22, 2019 Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.
Miller MM, Banville J, Friends TJ, Gagnon M, Hangeland JJ, Lavallée JF, Martel A, O'Grady H, Rémillard R, Ruediger E, Tremblay F, Posy SL, Allegretto NJ, Guarino VR, Harden DG, Harper TW, Hartl K, Josephs J, Malmstrom S, Watson C, Yang Y, Zhang G, Wong P, Yang J, Bouvier M, Seiffert DA, Wexler RR, Lawrence RM, Priestley ES, Marinier A
J. Med. Chem. 2019-08-22 ;62( 16 ):7400-7416. - See all publications