Application of chemical analysis techniques to study and manipulate biological systems. Determination of the structure of biological macromolecules and understanding of how alterations of these structures affect their functions.
Principal Investigators
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Vincent Archambault
Cell Cycle Regulation
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Katherine Borden
Structure and Function of the Cell Nucleus
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Delphine Bouilly
Design and Application of Electronic Nanobiosensors
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Michel Bouvier
Molecular Pharmacology
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Anne Marinier
Drug Discovery
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Matthew Smith
Cancer Signalling and Structural Biology
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Marc Therrien
Intracellular Signalling
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Pierre Thibault
Proteomics and Mass Spectrometry
Publications
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August 21, 2024 A Novel Confocal Scanning Protein-Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Interaction between the E2 Ubiquitin-Conjugating Enzyme CDC34A and Ubiquitin.
Koszela J, Pham NT, Shave S, St-Cyr D, Ceccarelli DF, Orlicky S, Marinier A, Sicheri F, Tyers M, Auer M
Bioconjug Chem 2024-08-21 ; - See all publications