Research field

Chemical & Structural Biology

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Application of chemical analysis techniques to study and manipulate biological systems. Determination of the structure of biological macromolecules and understanding of how alterations of these structures affect their functions.

Principal Investigators

  • Vincent Archambault

    Cell Cycle Regulation

  • Katherine Borden

    Structure and Function of the Cell Nucleus

  • Delphine Bouilly

    Design and Application of Electronic Nanobiosensors

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • April 2, 2024

    Pharmacological fingerprint of antipsychotic drugs at the serotonin 5-HT2A receptor.

    Gaitonde SA, Avet C, de la Fuente Revenga M, Blondel-Tepaz E, Shahraki A, Pastor AM, Talagayev V, Robledo P, Kolb P, Selent J, González-Maeso J, Bouvier M
    Mol Psychiatry 2024-04-02 ;

  • March 22, 2024

    SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia.

    Moison C, Gracias D, Schmitt J, Girard S, Spinella JF, Fortier S, Boivin I, Mendoza-Sanchez R, Thavonekham B, MacRae T, Mayotte N, Bonneil E, Wittman M, Carmichael J, Ruel R, Thibault P, Hébert J, Marinier A, Sauvageau G
    Sci Adv 2024-03-22 ;10( 12 ):eadl4018

  • March 1, 2024

    EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors.

    Gross F, Mancini A, Breton B, Kobayashi H, Pereira PHS, Le Gouill C, Bouvier M, Schann S, Leroy X, Sabbagh L
    Commun Biol 2024-03-01 ;7( 1 ):250

  • See all publications