Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.
Principal Investigators
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David Knapp
Cellular Engineering
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Sébastien Lemieux
Functional and Structural Bioinformatics
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Vincent Quoc-Huy Trinh
Digital Histology and Advanced Pathology
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Alain Verreault
Chromosome Biogenesis
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Brian Wilhelm
High-Throughput Genomics
Publications
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July 2, 2024 Genetic deletion of JAM-C in pre-leukemic cells rewires leukemic stem cell gene expression program in AML.
Grenier JMP, Testut C, Bal M, Bardin F, De Grandis M, Gelsi-Boyer V, Vernerny J, Delahaye MC, Granjeaud S, Zemmour C, Spinella JF, Chavakis T, Mancini SJ, Boher JM, Hébert J, Sauvageau G, Vey N, Schwaller J, Hospital MA, Fauriat C, Aurrand-Lions MA
Blood Adv 2024-07-02 ; - See all publications