Research field

Genomics & Epigenetics

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Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Lemieux

    Functional and Structural Bioinformatics

  • Julie Lessard

    Chromatin Structure and Stem Cell Biology

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Guy Sauvageau

    Molecular Genetics of Stem Cells

  • Vincent Quoc-Huy Trinh

    Digital Histology and Advanced Pathology

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • November 16, 2023

    Differential spatial distribution of HNF4α isoforms during dysplastic progression of intraductal papillary mucinous neoplasms of the pancreas.

    Wong J, Trinh VQ, Jyotsana N, Baig JF, Revetta F, Shi C, Means AL, DelGiorno KE, Tan M
    Sci Rep 2023-11-16 ;13( 1 ):20088

  • November 13, 2023

    PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.

    Sachan V, Le Dévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Resiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG
    Metabolism 2023-11-13 ;150:155736

  • September 20, 2023

    CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.

    Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
    Blood Adv 2023-09-20 ;

  • See all publications