Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.
Principal Investigators
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David Knapp
Cellular Engineering
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Sébastien Lemieux
Functional and Structural Bioinformatics
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Vincent Quoc-Huy Trinh
Digital Histology and Advanced Pathology
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Alain Verreault
Chromosome Biogenesis
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Brian Wilhelm
High-Throughput Genomics
Publications
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November 13, 2023 PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.
Sachan V, Le Dévéhat M, Roubtsova A, Essalmani R, Laurendeau JF, Garçon D, Susan-Resiga D, Duval S, Mikaeeli S, Hamelin J, Evagelidis A, Chong M, Paré G, Chernetsova E, Gao ZH, Robillard I, Ruiz M, Trinh VQ, Estall JL, Faraj M, Austin RC, Sauvageau M, Prat A, Kiss RS, Seidah NG
Metabolism 2023-11-13 ;150:155736 -
September 20, 2023 CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
Blood Adv 2023-09-20 ; - See all publications