Research field

Targeted Therapies & Diagnostics

Identification of biological markers of cancer and development of new diagnostic tools. Development of new targeted therapies and innovative drugs against cancer.

Principal Investigators

  • Katherine Borden

    Structure and Function of the Cell Nucleus

  • Delphine Bouilly

    Design and Application of Electronic Nanobiosensors

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Louis Gaboury

    Histology and Molecular Pathology

  • Trang Hoang

    Hematopoiesis and Leukemia

  • Julie Lessard

    Chromatin Structure and Stem Cell Biology

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Guy Sauvageau

    Molecular Genetics of Stem Cells

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

  • Vincent Q. Trinh

    Digital Histology and Advanced Pathology

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • October 20, 2023

    The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae.

    Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H
    iScience 2023-10-20 ;26( 10 ):107726

  • September 20, 2023

    CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.

    Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
    Blood Adv 2023-09-20 ;

  • September 12, 2023

    Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption.

    Kho I, Demina EP, Pan X, Londono I, Cairo CW, Sturiale L, Palmigiano A, Messina A, Garozzo D, Ung RV, Mac-Way F, Bonneil E, Thibault P, Lemaire M, Morales CR, Pshezhetsky AV
    JCI Insight 2023-09-12 ;

  • See all publications