Research field

Targeted Therapies & Diagnostics

Identification of biological markers of cancer and development of new diagnostic tools. Development of new targeted therapies and innovative drugs against cancer.

Principal Investigators

  • Katherine Borden

    Structure and Function of the Cell Nucleus

  • Delphine Bouilly

    Design and Application of Electronic Nanobiosensors

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Louis Gaboury

    Histology and Molecular Pathology

  • Trang Hoang

    Hematopoiesis and Leukemia

  • Julie Lessard

    Chromatin Structure and Stem Cell Biology

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Guy Sauvageau

    Molecular Genetics of Stem Cells

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

  • Vincent Q. Trinh

    Digital histology and advanced pathology

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • March 3, 2023

    SUMO Proteomics Analyses Identify Protein Inhibitor of Activated STAT-Mediated Regulatory Networks Involved in Cell Cycle and Cell Proliferation.

    Li C, Boutet A, Pascariu CM, Nelson T, Courcelles M, Wu Z, Comtois-Marotte S, Emery G, Thibault P
    J Proteome Res 2023-03-03 ;22( 3 ):812-825

  • February 27, 2023

    The eukaryotic translation initiation factor eIF4E reprograms alternative splicing.

    Ghram M, Morris G, Culjkovic-Kraljacic B, Mars JC, Gendron P, Skrabanek L, Revuelta MV, Cerchietti L, Guzman ML, Borden K
    EMBO J 2023-02-27 ;e110496

  • February 21, 2023

    Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro.

    Li ASM, Homsi C, Bonneil E, Thibault P, Verreault A, Vedadi M
    Biochim Biophys Acta Gene Regul Mech 2023-02-21 ;1866( 2 ):194922

  • See all publications