Identification of biological markers of cancer and development of new diagnostic tools. Development of new targeted therapies and innovative drugs against cancer.
Principal Investigators
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Katherine Borden
Structure and Function of the Cell Nucleus
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Delphine Bouilly
Design and Application of Electronic Nanobiosensors
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Michel Bouvier
Molecular Pharmacology
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Sébastien Carréno
Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility
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Louis Gaboury
Histology and Molecular Pathology
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Etienne Gagnon
Cancer Immunobiology
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Trang Hoang
Hematopoiesis and Leukemia
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Anne Marinier
Drug Discovery
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Sylvain Meloche
Signalling and Cell Growth
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Philippe P. Roux
Cell Signaling and Proteomics
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Claude Perreault
Immunobiology
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Marc Therrien
Intracellular Signalling
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Pierre Thibault
Proteomics and Mass Spectrometry
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Vincent Q. Trinh
Digital Histology and Advanced Pathology
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Brian Wilhelm
High-Throughput Genomics
Publications
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September 20, 2023 CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
Blood Adv 2023-09-20 ; -
September 12, 2023 Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption.
Kho I, Demina EP, Pan X, Londono I, Cairo CW, Sturiale L, Palmigiano A, Messina A, Garozzo D, Ung RV, Mac-Way F, Bonneil E, Thibault P, Lemaire M, Morales CR, Pshezhetsky AV
JCI Insight 2023-09-12 ; - See all publications